Author

M. Katz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 4 Organism:human· 3 Assay:electrophysiology· 2 Assay:proteomics· 2 Organism:Xenopus· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

N. Dascal· 3 shared O. Chomsky-Hecht· 3 shared A. Behrens· 2 shared A. Pinto-Fernandez· 2 shared B. M. Kessler· 2 shared C. Heride· 2 shared C. McKinnon· 2 shared D. Komander· 2 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersPhysiology

N. Dascal

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Tripartite interactions of PKA catalytic subunit and C-terminal domains of cardiac Ca2+ channel modulate its β-adrenergic regulation

S. Oz, T. Sharon, S. Surbramaniam, T. Pallien, M. Katz, V. Tsemakhovich, D. R. Tripathy, G. Sasson, O. Chomsky-Hecht, L. Vysochek, M. Schulz, C. Fecher-Trost, K. Zuhlke, D. Bertinetti, F. W. Herberg, , N. Dascal

This study identifies direct interactions between PKA catalytic subunit and C-terminal domains of cardiac CaV1.2 channels, revealing their role in modulating β-adrenergic regulation.

bioRxiv · Nov 28, 2023 · PreprintBiochemistry

Mapping molecular determinants of Cav2.2 inhibition by RGK proteins and homologs in Xenopus oocytes

Y. Sasson, S. Subramaniam, T. Buki, L. Almagor, O. Chomsky-Hecht, M. Katz, H. Puhl, S. R. Ikeda, N. Dascal, J. Hirsch

This study identifies structural determinants in RGK proteins that inhibit CaV2.2 channels in Xenopus oocytes, showing key regions in the G-domain and C-terminus are critical for this inhibition.

bioRxiv · Jun 21, 2022 · PreprintPhysiology

Reconstitution of β-adrenergic regulation of CaV1.2: Rad-dependent and Rad-independent protein kinase A mechanisms.

M. Katz, S. Subramaniam, O. Chomsky-Hecht, V. Tsemakhovich, A. Belkacemi, V. Flockerzi, E. Klussmann, J. Hirsch, S. Weiss, N. Dascal

This study reconstitutes the β-adrenergic regulation of CaV1.2 channels in a heterologous system, identifying Rad-dependent and Rad-independent PKA mechanisms.

bioRxiv · Nov 30, 2020Physiology

USP28 deletion and small molecule inhibition destabilises c-Myc and elicits regression of squamous cell lung carcinoma

E. J. Ruiz, A. Pinto-Fernandez, A. P. Turnbull, L. Lan, T. M. Charlton, H. C. Scott, A. Damianou, G. Vere, E. M. Riising, C. Da Costa, W. W. Krajewski, D. Guerin, J. Kearns, S. Ioannidis, M. Katz, , A. Behrens

This study shows that deleting or inhibiting USP28 reduces c-Myc levels and causes regression of lung squamous cell carcinoma in mice and human xenografts.

bioRxiv · Nov 17, 2020Cancer Biology

Coronacept - a potent immunoadhesin against SARS-CoV-2

H. Cohen-Dvashi, J. Weinstein, M. Katz, M. Eilon, Y. Mor, A. Shimon, R. Strobelt, M. Shemesh, S. J. Fleishman, R. Diskin

The paper describes the design of a modified human ACE2 immunoadhesin with enhanced affinity for SARS-CoV-2 spike protein, showing its potential as an antiviral agent.

bioRxiv · Aug 12, 2020 · PreprintBioengineering

The deubiquitylase USP9X controls ribosomal stalling

A. Clancy, C. Heride, A. Pinto-Fernandez, A. Kallinos, K. Kayser-Bricker, W. Wang, V. Smith, H. Elcocks, S. Davis, S. Fessler, C. McKinnon, M. Katz, T. Hammonds, N. P. Jones, J. O'Connell, , M. J. Clague

This study identifies USP9X as a deubiquitylase that regulates ZNF598 stability, impacting ribosomal quality control through modulation of di-ribosome resolution.

bioRxiv · Apr 15, 2020Cell Biology