Author

M. Toi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 3 Organism:human· 3 Organism:mouse· 3 Approach:statistical model· 2

Frequent Co-Authors

K. Kawaguchi· 4 shared C. He· 3 shared S. Kawaoka· 3 shared A. Vandenbon· 2 shared M. Yoda· 2 shared R. Konishi· 2 shared Y. Maeshima· 2 shared Y. Nakamura· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersCancer Biology

K. Kawaguchi

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5 papers

Recent·Most cited

Low albumin status accompanies multi-layered immunosuppressive phenotypes in metastatic breast cancer patients

Y. Nakamura, M. Yoda, Y. Izumi, Y. Kashima, M. Takahashi, K. Nakatani, T. Bamba, C. He, R. Konishi, D. P. Saldajeno, A. Vandenbon, Y. Suzuki, M. Toi, K. Kawaguchi, S. Kawaoka

The paper investigates the association between low albumin levels and immunosuppressive phenotypes in metastatic breast cancer patients using transcriptomic and metabolomic data.

bioRxiv · Sep 5, 2023 · PreprintCancer Biology

Selective elimination of CD169+ macrophages in lymph nodes invaded by breast cancers

Y. Maeshima, T. R. Kataoka, A. Vandenbon, M. Hirata, Y. Takeuchi, Y. Suzuki, Y. Fukui, Y. Ibi, H. Haga, S. Morita, M. Toi, S. Kawaoka, K. Kawaguchi

This study shows metastasized breast cancer cells eliminate CD169+ macrophages from lymph nodes, impairing anti-cancer immunity.

bioRxiv · Aug 2, 2023 · PreprintCancer Biology

Senescence triggers intracellular acidification and lysosomal alkalinization via ATP6AP2 attenuation in breast cancer cells

W. Li, K. Kawaguchi, S. Tanaka, C. He, Y. Maeshima, E. Suzuki, M. Toi

This study shows that ATP6AP2 downregulation in senescent breast cancer cells causes pH dysregulation, impairing lysosome function and altering immune responses.

bioRxiv · Apr 8, 2023 · PreprintCancer Biology

Serum amyloid alpha 1-2 are not required for systemic inflammation in the 4T1 murine breast cancer model

C. He, R. Konishi, A. Harata, Y. Nakamura, R. Mizuno, M. Yoda, M. Toi, K. Kawaguchi, S. Kawaoka

This study shows that SAA1-2 proteins are not essential for systemic inflammation in the 4T1 murine breast cancer model.

bioRxiv · Sep 26, 2022 · PreprintCancer Biology

Estrogen induces mammary ductal dysplasia.

J. Itou, R. Takahashi, H. Sasanuma, M. Tsuda, S. Morimoto, Y. Matsumoto, T. Ishii, F. Sato, S. Takeda, M. Toi

This study shows estrogen can cause mammary ductal dysplasia in a mouse model and demonstrates that isoflavones can inhibit this effect.

bioRxiv · Jun 18, 2019 · PreprintCancer Biology