Author

S. Kawaoka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:human· 2

Frequent Co-Authors

Y. Suzuki· 4 shared A. Vandenbon· 3 shared K. Kawaguchi· 3 shared M. Toi· 3 shared M. Yoda· 3 shared R. Konishi· 3 shared R. Mizuno· 3 shared C. He· 2 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

Y. Suzuki

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Low albumin status accompanies multi-layered immunosuppressive phenotypes in metastatic breast cancer patients

Y. Nakamura, M. Yoda, Y. Izumi, Y. Kashima, M. Takahashi, K. Nakatani, T. Bamba, C. He, R. Konishi, D. P. Saldajeno, A. Vandenbon, Y. Suzuki, M. Toi, K. Kawaguchi, S. Kawaoka

The paper investigates the association between low albumin levels and immunosuppressive phenotypes in metastatic breast cancer patients using transcriptomic and metabolomic data.

bioRxiv · Sep 5, 2023 · PreprintCancer Biology

Selective elimination of CD169+ macrophages in lymph nodes invaded by breast cancers

Y. Maeshima, T. R. Kataoka, A. Vandenbon, M. Hirata, Y. Takeuchi, Y. Suzuki, Y. Fukui, Y. Ibi, H. Haga, S. Morita, M. Toi, S. Kawaoka, K. Kawaguchi

This study shows metastasized breast cancer cells eliminate CD169+ macrophages from lymph nodes, impairing anti-cancer immunity.

bioRxiv · Aug 2, 2023 · PreprintCancer Biology

Murine breast cancers disorganize the liver transcriptome in zonated manners

A. Vandenbon, R. Mizuno, R. Konishi, M. Onishi, K. Masuda, Y. Kobayashi, H. Kawamoto, A. Suzuki, M. Shimizu, Y. Tanaka, Y. Suzuki, S. Kawaoka

This study uses spatial transcriptomics to show that breast cancers disrupt liver zonation patterns, affecting specific metabolic and immune pathways in a zonated manner.

bioRxiv · Sep 27, 2022Cancer Biology

Serum amyloid alpha 1-2 are not required for systemic inflammation in the 4T1 murine breast cancer model

C. He, R. Konishi, A. Harata, Y. Nakamura, R. Mizuno, M. Yoda, M. Toi, K. Kawaguchi, S. Kawaoka

This study shows that SAA1-2 proteins are not essential for systemic inflammation in the 4T1 murine breast cancer model.

bioRxiv · Sep 26, 2022 · PreprintCancer Biology

Nicotinamide-N-methyltransferase is essential for SAM and 1-methylnicotinamide homeostasis in the AML12 hepatocyte cell line

M. Yoda, R. Mizuno, I. Yoshihiro, M. Takahashi, T. Bamba, S. Kawaoka

This study investigates the role of NNMT in regulating SAM and MNAM metabolism in AML12 hepatocytes, finding that NNMT is a significant consumer of SAM and critical for MNAM production.

bioRxiv · Sep 25, 2022 · PreprintBiochemistry

A novel zebrafish intestinal tumor model reveals a role for cyp7a1-dependent tumor-liver crosstalk in tumor's adverse effects on host

S. Enya, K. Kawakami, Y. Suzuki, S. Kawaoka

This study establishes a zebrafish intestinal tumor model and identifies cyp7a1 as a host gene involved in tumor-induced liver inflammation through bile acid metabolism disruption.

bioRxiv · Oct 6, 2017Cancer Biology