Author

Mary Plascencia

Oregon Health & Science University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

allura thompsoniD· 2 shared Carmen Methner· 2 shared Fuying GaoiD· 2 shared Jeffrey S. Aaronson· 2 shared Jim Rosinski· 2 shared Lalini RamanathaniD· 2 shared Lijuan Liu· 2 shared Nan WangiD· 2 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersPhysiology

allura thompsonORCID

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Author profile →

4 papers

Recent·Most cited

Selective Pharmacological Blockade of GPR39 Markedly Reduces No Reflow and Infarct Volumes in a Rat Acute Myocardial Infarction When Administered Prior to Reperfusion

Carmen Methner, Mary Plascencia, allura thompson, Lijuan Liu, Masaki Kajimoto, D. Elizabeth Le, Agostino Cianciulli, Annalisa Pellacani, Jessica Franchi, chiara marcheselli, Alberto Parazzoli, Fabrizio Micheli, Sanjiv Kaul

Single intravenous bolus of the GPR39 antagonist VC108 shrank infarct and no-reflow volumes in rat myocardial infarction when given before reperfusion, but not 30 min after reperfusion.

bioRxiv · Aug 14, 2026 · PreprintPhysiology✦ In-depth digest

Deletion of GPR39 Prevents Pulmonary Arterial Hypertension by Attenuating Hypoxia-Induced Aberrant Signaling

Carmen Methner, Lijuan Liu, allura thompson, Mary Plascencia, Priyanka Chakravarty, Sanjiv Kaul

This study shows that deleting GPR39 prevents pulmonary arterial hypertension by reducing hypoxia-induced signaling and vascular remodeling.

bioRxiv · Jul 2, 2026 · PreprintPhysiology

Large-scale Perturbation of Systems Biology-Derived Genes Reveals Modifiers of HD-associated Transcriptomic Networks and Pathology

Peter Langfelder, Nan Wang, Lalini Ramanathan, Young Mi Oh, Seongwon Lee, Fuying Gao, Xiaofeng Gu, Matthew Stricos, Mary Plascencia, Raymond Vaca, Jeffrey Richman, Thomas Vogt, Steve Horvath, Andrew S.J. Yoo, Jeffrey S. Aaronson, , X. William Yang

The paper uses genetic perturbations to identify modifiers of HD-associated transcriptomic networks and pathology in mice and patient-derived neurons.

bioRxiv · Mar 4, 2026 · PreprintGenetics

Msh3 and Pms1 Set Neuronal CAG-repeat Migration Rate to Drive Selective Striatal and Cortical Pathogenesis in HD Mice

Nan Wang, Shasha Zhang, Peter Langfelder, Lalini Ramanathan, Mary Plascencia, Fuying Gao, Raymond Vaca, Xiaofeng Gu, Linna Deng, Leonardo E. Dionisio, Brinda C. Prasad, Thomas Vogt, Steve Horvath, Jeffrey S. Aaronson, Jim Rosinski, X. William Yang

This study identifies Msh3 and Pms1 as genetic drivers of CAG-repeat migration in HD mice, leading to selective striatal and cortical pathogenesis.

bioRxiv · Jul 9, 2024 · PreprintNeuroscience