Meera Gupta

Nepali oral microbiomes reflect a gradient of lifestyles from traditional to industrialized

This study examines oral microbiomes of Nepali individuals with different lifestyles, finding that lifestyle, not geography, shapes microbiome composition across a gradient from foraging to industrialized.

Differential nuclear import sets the timing of protein access to the embryonic genome

The paper identifies that differential nuclear import timing controls gene expression onset in early embryonic development by regulating protein access to the genome.

Gut bacterial nutrient preferences quantified in vivo

The paper quantifies nutrient preferences of gut bacteria in mice using isotope tracing and finds dietary fiber, protein, and host-derived metabolites drive microbial growth.

Global Protein-Turnover Quantification in Escherichia coli Reveals Cytoplasmic Recycling under Nitrogen-Limitation

The paper quantifies protein turnover in E. coli under 12 conditions, revealing cytoplasmic protein recycling under nitrogen limitation and identifying unknown proteolysis pathways.

Evaluating the Simple Arrhenius Equation for the Temperature Dependence of Complex Developmental Processes

This study evaluates the Arrhenius equation's ability to predict temperature dependence in complex developmental processes like frog and fruit fly embryogenesis, finding it provides a good approximation despite deviations at extreme temperatures.

Precise temporal regulation of post-transcriptional repressors is required for an orderly Drosophila maternal-to-zygotic transition

The paper shows that precise degradation of post-transcriptional repressors during the Drosophila MZT is essential for orderly transition to zygotic gene control.

Bayesian Confidence Intervals for Multiplexed Proteomics Integrate Ion-Statistics with Peptide Quantification Concordance

The paper introduces BACIQ, a method to calculate confidence intervals for multiplexed proteomics data by integrating peptide signal and measurement agreement, improving the detection of subcellular protein movement.