Author

P. D. Rogers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. L. Kelly· 3 shared C. A. Cuomo· 2 shared J. F. Munoz· 2 shared J. M. Rybak· 2 shared J. Parker· 2 shared K. S. Barker· 2 shared A. Abdullah· 1 shared B. D. Esquivel· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMicrobiology

S. L. Kelly

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3 papers

Recent·Most cited

In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris

J. M. Rybak, K. S. Barker, J. F. Munoz, J. E. Parker, S. Ahmad, E. Mokaddas, A. Abdullah, R. S. Elhagracy, S. L. Kelly, C. A. Cuomo, P. D. Rogers

The paper identifies a mutation in the ERG6 gene as the first mechanism of amphotericin B resistance in Candida auris, observed during in vivo treatment.

bioRxiv · Oct 8, 2021Microbiology

Loss-of-function ROX1 mutations suppress the fluconazole susceptibility of upc2AΔ mutation in Candida glabrata, implicating additional positive regulators of ergosterol biosynthesis

T. L. Ollinger, B. Vu, D. Murante, J. Parker, L. Simonicova, L. A. Doorley, M. A. Stamnes, S. L. Kelly, P. D. Rogers, W. S. Moye-Rowley, D. J. Krysan

The paper identifies ROX1 as a negative regulator of ergosterol biosynthesis genes in C. glabrata and shows that its loss-of-function suppresses fluconazole hypersusceptibility in upc2AΔ mutants.

bioRxiv · Oct 7, 2021 · PreprintMicrobiology

Mutations in TAC1B: a novel genetic determinant of clinical fluconazole resistance in C. auris

J. M. Rybak, J. F. Munoz, K. S. Barker, J. Parker, B. D. Esquivel, E. L. Berkow, S. R. Lockhart, L. Gade, G. E. Palmer, T. C. White, S. L. Kelly, C. A. Cuomo, P. D. Rogers

This paper identifies mutations in TAC1B as a novel genetic determinant of clinical fluconazole resistance in C. auris, showing their contribution to resistance through increased CDR1 expression and functional validation.

bioRxiv · Feb 18, 2020Microbiology