R. Chen

This study identifies circ_0005962 as an oncogene in NSCLC that promotes progression via the circ_0005962/miR-382-5p/PDK4 regulatory network.

The paper describes a Cretaceous insect with exaggerated leaf-like antennae, suggesting sensory organs played a significant role in sexual selection and evolutionary trade-offs.

The paper evaluates three 16S rRNA sequencing protocols for vaginal microbiome analysis and identifies biases in species abundance estimation, proposing an optimized protocol to improve accuracy.

This study identifies lncRNA AVAN as a positive regulator of antiviral innate immunity by interacting with TRIM25 and enhancing FOXO3a transcription.

This paper develops a deep learning model to analyze heterogeneous intracellular transport by estimating Hurst exponents from short time series data, enabling dynamic segmentation of cellular structures.

The paper identifies CLN6 and the EGRESS complex as essential for lysosomal enzyme trafficking from the ER to the Golgi, revealing their role in Batten disease pathogenesis.

This study characterizes the structural and biochemical interactions of the MazEF-mt9 TA system in M. tb, revealing its cognate and heterologous antitoxin binding and its role in stress adaptation.

The paper identifies genetic and transcriptional features of basal-like subtypes in pancreatic ductal adenocarcinoma, linking them to squamous histology and chromatin modifier mutations.

This study shows that gut microbiota influences biliary regenerative responses in mice, with butyrate playing a role in inhibiting fibrosis.

This study identifies a novel signaling loop involving ADAMDEC1 and FGF2/FGFR1 that maintains glioblastoma cancer stem cells and shows targeting this loop reduces tumor growth.

This study examines microbial interactions in asthma airways, finding increased bacterial and fungal diversity and significant associations between Moraxellaceae, Moraxella, and the airway mycobiome.

The paper improves in vitro culture conditions for Schistosoma mansoni, enabling sustained egg production and revealing male-induced female maturation and a novel nuclear receptor involved in sexual development.

The paper investigates nuclear germ granules in Drosophila PGCs, showing Oskar drives their formation and function in cell division.

This paper develops a computational model showing that ecology and social interactions alone can drive task specialization in social insect colonies, with weak specialization being more adaptive in dynamic environments.

This study identifies outer membrane vesicles from Lysobacter enzymogenes C3 as vehicles for delivering antifungal antibiotics to fungal targets.

This study shows that targeting the HIV-1 fusion peptide with specific immunogens induces cross-clade neutralizing antibodies in animals.

This study identifies 208 imprinted genes in rice, showing limited transposable element association, intraspecific variation, and conservation of imprinting at some loci across plant species.