Author

R. Kise

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Inoue· 3 shared K. Kawakami· 2 shared A. K. SHUKLA· 1 shared A. Ranjan· 1 shared B. Barsi-Rhyne· 1 shared B. K. Kobilka· 1 shared C. Cui· 1 shared C. Suno-Ikeda· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBiochemistry

A. Inoue

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural and Dynamic Insights into the Biased Signaling Mechanism of the Human Kappa Opioid Receptor

C. Suno-Ikeda, R. Nishikawa, R. Suzuki, S. Iwata, T. Takai, T. Ogura, M. Hirose, A. Inoue, E. Asai, R. Kise, Y. Sugita, T. Kato, H. Nagase, T. Saito, K. Katayama, , R. Suno

This study investigates the structural dynamics of the human KOR-Gi signaling complex with G-protein-biased and balanced agonists, identifying key residues involved in signaling bias.

bioRxiv · Apr 11, 2024 · PreprintBiophysics

Membrane phosphoinositides stabilize GPCR-arrestin complexes and offer temporal control of complex assembly and dynamics

J. Janetzko, R. Kise, B. Barsi-Rhyne, D. H. Siepe, F. M. Heydenreich, M. Masureel, K. Kawakami, K. C. Garcia, M. Von Zastrow, A. Inoue, B. K. Kobilka

This study identifies membrane phosphoinositides as regulators of GPCR-arrestin complex dynamics, showing they stabilize complexes and enable temporal control of receptor signaling and recycling.

bioRxiv · Oct 9, 2021Biochemistry

Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors

S. Pandey, P. Kumari, M. Baidya, R. Kise, Y. Cao, H. Dwivedi-Agnihotri, R. Banerjee, X. Li, C. Cui, J. Lee, K. Kawakami, M. Chaturvedi, A. Ranjan, S. Laporte, T. M. Woodruff, , A. K. SHUKLA

The paper identifies two non-canonical GPCRs, D6R and C5aR2, that exclusively couple to β-arrestins and exhibit distinct GRK preferences and downstream signaling.

bioRxiv · Feb 2, 2021Biochemistry