Author

R. Le Borgne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Microbiology· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:cell signaling & trafficking· 6 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

J.-M. Verbavatz· 4 shared C. Durieu· 3 shared N. MINC· 3 shared A. Boudaoud· 2 shared A. Weiner· 2 shared A. Bouissou· 1 shared A. Burel· 1 shared A. Cheron· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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4 shared papersCell Biology

J.-M. Verbavatz

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Author profile →

9 papers

Recent·Most cited

Fascin-induced bundling protects actin filaments from disassembly by cofilin

J. Chikireddy, L. Lengagne, R. Le Borgne, H. Wioland, G. Romet-Lemonne, A. Jegou

This study shows that fascin crosslinking slows cofilin-induced actin filament disassembly by reducing cofilin cluster nucleation on bundles, while promoting inter-filament cooperativity.

bioRxiv · May 19, 2023Biochemistry

The ER tether VAPA is required for proper cell motility and anchors ER-PM contact sites to focal adhesions

H. Siegfried, R. Le Borgne, C. Durieu, T. De Azevedo Laplace, A. Verraes, L. Daunas, J.-M. Verbavatz, M. L. Heuze

This study shows that VAPA is essential for cell motility by anchoring ER-PM contact sites to focal adhesions and maintaining PI(4,5)P2 levels at the plasma membrane.

bioRxiv · Oct 17, 2022Cell Biology

Cell Wall Dynamics in a Filamentous Fungus

L. Chevalier, M. Pinar, R. Le Borgne, C. Durieu, M. Penalva, A. Boudaoud, N. MINC

The paper studies cell wall dynamics in Aspergillus nidulans using sub-resolution imaging and develops a mechanical model to explain how secretion and expansion balance to support tip growth and morphogenesis.

bioRxiv · Jun 12, 2022 · PreprintCell Biology

The AMA1-RON complex drives Plasmodium sporozoite invasion in the mosquito and mammalian hosts

P. Fernandes, M. Loubens, R. Le Borgne, C. Marinach, B. Ardin, S. Briquet, L. Vincensini, S. Hamada, B. Hoareau-Coudert, J.-M. Verbavatz, A. Weiner, O. Silvie

This study shows that the AMA1-RON complex is essential for Plasmodium sporozoite invasion of mosquito salivary glands and mammalian hepatocytes, supporting its role in parasite transmission.

bioRxiv · Jan 4, 2022Microbiology

Contribution of cytoplasm viscoelastic properties to mitotic spindle positioning

J. Xie, J. Najafi, R. Le Borgne, C. Durieu, J.-M. Verbavatz, J. Salle, N. Minc

This study shows that cytoplasm viscoelastic properties can actively move and reposition mitotic spindles in living cells, independent of cytoskeletal forces.

bioRxiv · Oct 21, 2021Cell Biology

Trans-cellular tunnels induced by the fungal pathogen Candida albicans facilitate invasion through successive epithelial cells without host damage

J. Lachat, A. Pascault, D. Thibaut, R. Le Borgne, J.-M. Verbavatz, A. Weiner

This study shows Candida albicans invades epithelial cells through trans-cellular tunnels, either causing or avoiding host damage, using live-cell imaging and electron microscopy.

bioRxiv · Sep 9, 2021Microbiology

Mitochondrial Aurora kinase A induces mitophagy by interacting with MAP1LC3 and Prohibitin 2

G. Bertolin, M.-C. Alves-Guerra, A. Cheron, A. Burel, C. Prigent, R. Le Borgne, M. Tramier

This study identifies AURKA's role in inducing mitophagy via a tripartite complex with PHB2 and MAP1LC3, and shows that Xanthohumol can block this process.

bioRxiv · Apr 6, 2020Cell Biology

Super-resolved live-cell imaging using Random Illumination Microscopy

T. Mangeat, S. Labouesse, M. Allain, R. Poincloux, A. Bouissou, S. Cantaloube, E. Courtais, E. Vega, T. Li, A. Guenole, C. Rouviere, S. Allard, N. Campo, M. Suzanne, X. Wang, , A. Sentenac

This paper introduces Random Illumination Microscopy (RIM), a super-resolution technique that achieves high-resolution, low-toxicity, and fast imaging for live-cell studies.

bioRxiv · Jan 27, 2020Bioengineering

MECHANOSENSATION DYNAMICALLY COORDINATES POLAR GROWTH AND CELL WALL ASSEMBLY TO PROMOTE CELL SURVIVAL

V. Davi, H. Tanimoto, D. Ershov, A. Haupt, H. De Belly, R. Le Borgne, E. Couturier, A. Boudaoud, N. Minc

This study identifies a feedback mechanism that coordinates polar growth and cell wall assembly in fission yeast to maintain wall thickness and cell survival.

bioRxiv · Apr 10, 2018Cell Biology