Author

R. M. Parton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Bioengineering· 1 Biophysics· 1 Microbiology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Assay:fluorescence / live-cell microscopy· 5 Assay:imaging· 3 Organism:Drosophila· 2 Research Focus:imputation· 2 Approach:microscopy & imaging analysis· 2 Assay:spatial transcriptomics· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

I. Davis· 8 shared I. M. Dobbie· 5 shared M. A. Phillips· 4 shared M. J. Booth· 4 shared D. M. S. Pinto· 3 shared A. Castello· 2 shared A. Palanca· 2 shared D. Gala· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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8 shared papersCell Biology

I. Davis

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Deep3DSIM: Super-resolution imaging of thick tissue using 3D structured illumination with adaptive optics

J. Wang, D. Stoychev, M. Phillips, D. M. S. Pinto, R. M. Parton, N. Hall, J. Titlow, A. R. Faria, M. Wincott, D. Gala, A. Gerondopoulos, N. Irani, I. Dobbie, L. Schermelleh, M. Booth, I. Davis

This paper introduces Deep3DSIM, an upright 3D-SIM system with adaptive optics for deep tissue imaging, achieving high-quality imaging up to 130 micrometers in Drosophila brain.

bioRxiv · Dec 21, 2023Cell Biology

Systematic analysis of YFP gene traps reveals common discordance between mRNA and protein across the nervous system

J. S. Titlow, M. Kiourlappou, A. Palanca, J. Y. Lee, D. S. Gala, D. Ennis, J. J. S. Yu, F. L. Young, D. M. S. Pinto, S. Garforth, H. S. Francis, F. Strivens, H. Mulvey, A. Dallman-Porter, S. Thornton, , I. Davis

The paper systematically analyzes YFP gene traps in Drosophila to show widespread discordance between mRNA and protein expression in the nervous system, revealing common post-transcriptional regulation.

bioRxiv · Mar 21, 2022 · PreprintCell Biology

Absolute quantitation of individual SARS-CoV-2 RNA molecules: a new paradigm for infection dynamics and variant differences

J. Y. Lee, P. A. Wing, D. S. Gala, M. Noerenberg, A. I. Jarvelin, J. Titlow, X. Zhuang, N. Palmalux, L. Iselin, M. K. Thompson, R. M. Parton, A. Wainman, D. Agranoff, W. James, A. Castello, , I. Davis

The paper quantifies SARS-CoV-2 RNA molecules using smFISH, revealing genomic RNA stability, cell-to-cell replication variability, and slower replication kinetics for the B.1.1.7 variant compared to the Victoria strain.

bioRxiv · Jun 29, 2021Microbiology

Microscope-Cockpit: Python-based bespoke microscopy for bio-medical science

M. A. Phillips, D. M. Susano Pinto, N. Hall, J. Mateos-Langerak, R. M. Parton, D. V. Stoychev, T. Park, T. S. Pinto, J. W. Sedat, M. J. Booth, I. Davis, I. M. Dobbie

The paper introduces Microscope-Cockpit, a Python-based GUI for controlling bespoke microscopes, enabling efficient specimen navigation and hardware integration through open-source tools.

bioRxiv · Jan 18, 2021Biophysics

Wavefront-sensorless adaptive optics with a laser-free spinning disk confocal microscope

S. A. Hussain, T. Kubo, N. J. Hall, D. Gala, K. Hampson, R. M. Parton, M. A. Phillips, M. Wincott, K. Fujita, I. Davis, I. M. Dobbie, M. J. Booth

The paper introduces wavefront-sensorless adaptive optics for a laser-free spinning disk confocal microscope, improving signal, contrast, and resolution by correcting specimen-induced aberrations.

bioRxiv · Jul 28, 2020Cell Biology

Democratising "Microscopi": a 3D printed automated XYZT fluorescence imaging system for teaching, outreach and fieldwork

M. B. Wincott, A. Jefferson, I. M. Dobbie, M. J. Booth, I. Davis, R. M. Parton

The paper describes a low-cost, 3D-printed automated fluorescence imaging system for teaching and outreach, demonstrating its multimodal imaging capabilities and open-source design.

bioRxiv · May 21, 2020Scientific Communication & Education

CryoSIM: super resolution 3D structured illumination cryogenic fluorescence microscopy for correlated ultra-structural imaging

M. A. Phillips, M. Harkiolaki, D. M. S. Pinto, R. M. Parton, A. Palanca, M. Garcia-Moreno, I. Kounatidis, J. Sedat, D. I. Stuart, A. Castello, M. J. Booth, I. Davis, I. M. Dobbie

The paper introduces cryoSIM, a super-resolution 3D fluorescence microscope for cryo-imaging that can be replicated with off-the-shelf components and open-source software.

bioRxiv · Mar 9, 2020Cell Biology

IsoSense: frequency enhanced sensorless adaptive optics through structured illumination

M. Zurauskas, I. M. Dobbie, R. M. Parton, M. A. Phillips, A. Gohler, I. Davis, M. Booth

IsoSense improves sensorless adaptive optics by using structured illumination to enhance spatial frequencies for reliable wavefront sensing in microscopy.

bioRxiv · Jan 24, 2019Bioengineering