Author

K. Yoo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

j. choi· 3 shared J. Jeong· 2 shared J. Lee· 2 shared J. Shin· 2 shared J. Wysolmerski· 2 shared L. K. Kim· 2 shared A. Gopalan· 1 shared A. Haberman· 1 shared

Activity by Year

2021-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCancer Biology

j. choi

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Author profile →

6 papers

Recent·Most cited

The eIF3a subunit drives RNA binding within the eIF3 complex

N. A. Ide, R. C. Gentry, B. Ashwood, M. A. Rudbach, K. Yoo, P. K. Velez, V. M. Communale, E. W. Hartwick, C. D. Kinz-Thompson, R. L. Gonzalez, C. E. Aitken

This study reconstitutes a biochemically active yeast eIF3 complex and shows that eIF3a provides core RNA-binding activity, modulated by interactions with other subunits.

bioRxiv · Apr 25, 2024 · PreprintBiophysics

A FOXA1/SPDEF Co-regulatory Axis Drives ERBB2 and Suppresses TEAD/YAP-Driven EMT to Maintain Luminal Identity in HER2+ Breast Cancer

J. Jeong, J. Lee, S. Kim, J. Lim, J. Shin, K. Yoo, J. Kim, Y. Tanaka, H. S. Tae, L. K. Kim, I.-H. Park, J. Wysolmerski, j. choi

This study identifies a FOXA1/SPDEF co-regulatory axis that drives ERBB2 expression and suppresses EMT in HER2+ breast cancer, maintaining luminal identity and serving as a therapeutic target.

bioRxiv · Apr 16, 2024 · PreprintCancer Biology

The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1

R. Romero, T. Chu, T. J. Gonzalez-Robles, P. Smith, Y. Xie, H. Kaur, S. Yoder, H. Zhao, C. Mao, W. Kang, M. Pulina, K. E. Lawrence, A. Gopalan, S. Zaidi, K. Yoo, , C. Sawyers

This study identifies ASCL1 as a critical driver of neuroendocrine lineage transition in prostate cancer using an in vivo model and spatial transcriptomics.

bioRxiv · Apr 9, 2024Cancer Biology

Achieving Resilience in Aging: How Mitochondrial Modulation Drives Age-associated Fluconazole Tolerance in Cryptococcus neoformans

K. Yoo, N. K. Oliveira, S. Bhattacharya, B. C. Fries

This study identifies mitochondrial metabolic changes in old Cryptococcus neoformans cells that drive fluconazole tolerance through increased ergosterol synthesis and ABC transporter upregulation.

bioRxiv · Mar 26, 2024 · PreprintMicrobiology

Intracellular Calcium links Milk Stasis to Lysosome Dependent Cell Death by Activating a TGFbeta3/TFEB/STAT3 Pathway Early during Mammary Gland Involution

J. JEONG, J. Lee, G. Talaia, W. Kim, J. Song, J. Hong, K. Yoo, D. Gonzalez, D. Athonvarangkul, J. Shin, P. Dann, A. Haberman, L. K. Kim, S. Ferguson, J. Choi, J. Wysolmerski

The paper shows that intracellular calcium, triggered by milk stasis, activates STAT3 via SOCS3 degradation and TFEB, leading to lysosome-dependent cell death during mammary gland involution.

bioRxiv · May 17, 2022 · PreprintCell Biology

Invasive Earthworms Alter Forest Soil Microbiomes and Nitrogen Cycling

J. Jang, X. Xiong, C. Liu, K. Yoo, S. Ishii

This study shows invasive earthworms alter soil microbiomes and shift nitrogen cycling from nitrification to denitrification in hardwood forests.

bioRxiv · Mar 7, 2021Microbiology