Author

S. Balachandran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Genetic & Genomic Medicine· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

K. Devarajan· 2 shared K. Q. Cai· 2 shared S. Peri· 2 shared Y. Zhou· 2 shared A. Alcami· 1 shared A. Bellacosa· 1 shared A. Hait· 1 shared A. Herengt· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

K. Devarajan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

HiFi sequencing accurately identifies clinically relevant variants in paralogous genes

B. van der Sanden, C. Betz, K. Herzog, Esther Schamschula, K. Wimmer, Ira Vater, S. Balachandran, Jordi Corominas, Raoul Timmermans, Ronny C. Derks, M. Spielmann, MA Eberle, C.F.H.A. Gilissen, L.E.L.M. Vissers, Johannes Zschocke, , Alexander Hoischen

This study shows that PacBio HiFi long-read sequencing with Paraphase variant caller detects all clinically relevant variants in paralogous regions, improving variant calling accuracy.

The American Journal of Human Genetics · Jun 1, 2026Peer-reviewedGenetic & Genomic Medicine

Identification of SARS-CoV2-mediated suppression of NRF2 signaling reveals a potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

D. Olagnier, E. Farahani, J. Thyrsted, J. B. Cadanet, A. Herengt, M. Idorn, A. Hait, B. Hernaez, A. Knudsen, M. B. Iversen, M. Schilling, S. E. Jorgensen, M. Thomsen, L. Reinert, M. Lappe, , C. K. Holm

The paper identifies NRF2 agonists 4-OI and DMF as inhibitors of SARS-CoV2 replication and inflammatory responses, effective against multiple viruses.

bioRxiv · Jul 16, 2020Microbiology

Netrin G1 promotes pancreatic tumorigenesis through cancer associated fibroblastdriven nutritional support and immunosuppression

R. Francescone, D. Barbosa Vendramini-Costa, J. Franco-Barraza, J. Wagner, A. Muir, A. N. Lau, L. Gabitova, T. Pazina, S. Gupta, T. Luong, N. Shah, D. Rollins, R. Malik, R. Thapa, D. Restifo, , E. Cukierman

This study identifies Netrin G1 as a promoter of pancreatic ductal adenocarcinoma tumorigenesis by enhancing cancer-associated fibroblast-driven metabolic support and immunosuppression.

bioRxiv · May 30, 2020Cancer Biology

TET1 and TDG suppress intestinal tumorigenesis by down regulating the inflammatory and immune response pathways

R. Tricarico, J. Madzo, G. Scher, S. Maegawa, J. Jelinek, C. Scher, W.-C. Chang, E. Nicolas, Y. Zhou, M. Slifker, K. Devarajan, K. Q. Cai, P. Nakajima, J. Xu, P. Mancuso, , A. Bellacosa

This study shows that TET1 and TDG reduce intestinal tumor formation by suppressing inflammatory and immune response pathways through DNA demethylation.

bioRxiv · Jun 21, 2019 · PreprintCancer Biology