Author

S. Takayama

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Plant Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 5 Organism:human· 4 Organism:Arabidopsis· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

E. Parigoris· 2 shared J.-H. Lee· 2 shared S. Fujii· 2 shared Y. Kato· 2 shared A. Li· 1 shared A. Monteiro da Rocha· 1 shared A. Shcherbina· 1 shared A. Y. Liu· 1 shared

Activity by Year

2022-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBioengineering

E. Parigoris

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Development of robust antiviral assays using relevant apical-out human airway organoids

J.-H. Lee, J. C. LeCher, E. Parigoris, N. Shinagawa, J. Sentosa, C. Manfredi, S. L. Goh, R. De, S. Tao, K. Zandi, F. Amblard, E. J. Sorscher, J. R. Spence, R. Tirouvanziam, R. F. Schinazi, S. Takayama

This paper develops AORBs, a high-throughput human airway organoid system, to robustly assess antiviral efficacy against SARS-CoV-2 with high throughput and clinical relevance.

bioRxiv · Jan 2, 2024 · PreprintBioengineering

Liquid plug propagation in computer-controlled microfluidic airway-on-a-chip with semi-circular microchannels

H. Viola, V. Vasani, K. Washington, J. H. Lee, C. Selva, A. Li, C. J. Llorente, Y. Murayama, J. B. Grotberg, F. Romano, S. Takayama

This paper presents a lung-on-a-chip device that enables systematic study of liquid plug dynamics in distal airways, showing effects of surfactant, viscosity, and channel geometry on plug propagation and epithelial cell injury.

bioRxiv · May 24, 2023Bioengineering

In depth amino acid mutational analysis of the key interspecific incompatibility transmembrane factor Stigmatic Privacy 1

Y. Kato, S. Tadokoro, S. Ishida, M. Niidome, Y. Kimura, S. Takayama, S. Fujii

The paper identifies key amino acid residues in SPRI1 critical for its function in interspecific incompatibility in Arabidopsis thaliana.

bioRxiv · Apr 11, 2023 · PreprintPlant Biology

Manipulation of the nucleoscaffold potentiates cellular reprogramming kinetics

B. A. Yang, A. Monteiro da Rocha, I. Newton, A. Shcherbina, S.-W. Wong, P. M. Fraczek, J. A. Larouche, H. L. Hiraki, B. M. Baker, J.-W. Shin, S. Takayama, M. D. Thouless, C. A. Aguilar

This study shows that manipulating Lamin A/C affects nuclear structure and reprogramming efficiency in human fibroblasts.

bioRxiv · Mar 12, 2023Cell Biology

A land plant specific VPS13 mediates polarized vesicle trafficking in germinating pollen

S. Tangpranomkorn, M. Igarashi, F. Ishizuna, Y. Kato, T. Suzuki, S. Fujii, S. Takayama

This study identifies AtVPS13a as a plant-specific protein required for directional vesicle trafficking during Arabidopsis pollen germination, linking it to pollen tube growth and cell wall deposition.

bioRxiv · Nov 1, 2022Plant Biology

Extended longevity geometrically-inverted proximal tubule organoids for protein uptake studies

E. Parigoris, J.-H. Lee, A. Y. Liu, X. Zhao, S. Takayama

This study develops geometrically-inverted proximal tubule organoids to better model proteinuric kidney disease by enabling apical surface access for protein uptake studies.

bioRxiv · Mar 24, 2022Bioengineering