Author

J. N. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Ecology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 3 Organism:human· 2 Assay:metagenomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1

Frequent Co-Authors

J. M. Leong· 2 shared A. Manjula-Basavanna· 1 shared A. Sheoran· 1 shared A. Shrestha· 1 shared A. Y. Na· 1 shared B. J. Wainwright· 1 shared B.-H. Park· 1 shared C. B. Shoemaker· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersMicrobiology

J. M. Leong

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The Mangrove Microbiome of the Malay Peninsula

B. J. Wainwright, K. J. E. Hickman, T. Millar, L. Bowen, J. N. Lee, Z. Y. Yeo, D. Huang, G. L. Zahn

This study examines the microbiome of mangrove trees in the Malay Peninsula, identifying a core microbiome and key taxa involved in nutrient cycling and carbon sequestration.

bioRxiv · Nov 21, 2022 · PreprintEcology

SIRT5 is the desuccinylase of LDHA as novel cancer metastatic stimulator in aggressive prostate cancer

O. K. Kwon, I. H. Bang, S. Y. Choi, J. M. Jeon, A. Y. Na, Y. Gao, S. S. Cho, S. H. Ki, Y. Chpe, J. N. Lee, Y.-S. Ha, E. Bae, T. G. Kwon, B.-H. Park, S. Lee

This study identifies SIRT5 as a desuccinylase that regulates LDHA succinylation, promoting prostate cancer metastasis and progression.

bioRxiv · Aug 8, 2021Cancer Biology

Single domain antibodies against enteric pathogen virulence factors are active as curli fiber fusions on probiotic E. coli Nissle 1917

I. Gelfat, Y. Aqeel, J. M. Tremblay, J. Jaskiewicz, A. Shrestha, J. N. Lee, S. Hu, X. Qian, L. Magoun, A. Sheoran, D. Bedenice, C. Giem, A. Manjula-Basavanna, M. S. Osbourne, S. Tzipori, , N. S. Joshi

The paper develops VHH-based therapeutics displayed on probiotic E. coli Nissle 1917 to target enteric pathogens, showing they can bind and neutralize virulence factors.

bioRxiv · Jun 18, 2021Microbiology

Extracellular adenosine enhances the ability of PMNs to kill Streptococcus pneumoniae by inhibiting IL-10 production

N. Siwapornchai, J. N. Lee, E. Y. I. Tchalla, M. Bhalla, J. Hui Yeoh, S. E. Roggensack, J. M. Leong, E. N. Bou Ghanem

The paper shows that extracellular adenosine, produced via CD73, enhances PMN killing of Streptococcus pneumoniae by inhibiting IL-10 production.

bioRxiv · Dec 8, 2019Immunology