Sex specific correction of maternal inflammation-induced behavioral abnormalities by the inhibition of colony-stimulating factor 1 receptor
Jean-Christophe Delpech, Hana Yeh, Srinidhi Venkatesan Kalavai, Yang You, Zhi Ruan, Nina Touch, Samuel Walter Hersh, Pauline Monguillon, William Evan Johnson, Andréa Rau, Charlotte Madore, Tsuneya Ikezu, Seiko Ikezu
This study shows that inhibiting CSF1R in male MIA offspring improves sociability and memory, while female offspring show no improvement, highlighting sex-specific therapeutic potential.
Brain Behavior and Immunity · Nov 3, 2025Peer-reviewedAnimal Behavior & Cognition