Maria Ericsson

Ancestral sequence reconstruction of the Mic60 Mitofilin domain reveals residues supporting respiration in yeast

This study uses ancestral sequence reconstruction to identify residues in the Mitofilin domain of Mic60 that support respiration in yeast.

Alpha-synuclein modulates the positioning of endolysosomes in melanoma cells

This study shows that alpha-synuclein modulates endolysosome positioning in melanoma cells, affecting invasion and migration by altering membrane protein levels and trafficking.

Functional Specialization of S-Adenosylmethionine Synthases Links Phosphatidylcholine to Mitochondrial Function and Stress Survival

The paper investigates the functional specialization of SAM synthases in C. elegans, showing that SAMS-1 affects mitochondrial function and stress survival through phosphatidylcholine, while SAMS-4 is critical for methylation reactions.

Abundant Aβ fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer's disease brains

The paper reports the presence of abundant Aβ fibrils in aqueous extracts from Alzheimer's disease brains, with structures identical to those in amyloid plaques.

Viral proteins and virus-like particles of the LTR5_Hs endogenous retrovirus in human primordial germ cell-like cells

The paper identifies LTR5_Hs viral proteins and virus-like particles in hPGCLCs, showing their activation during early germ cell development and suppression upon gonadal anlagen settlement.

Amyloid plaque deposition accelerates tau propagation via activation of microglia in a humanized APP mouse model

The paper shows that amyloid plaques accelerate tau propagation in mice by activating microglia, which secrete more extracellular vesicles.

Alzheimer's disease brain-derived tau-containing extracellular vesicles: Pathobiology and GABAergic neuronal transmission

This study investigates how Alzheimer's disease-derived extracellular vesicles propagate tau pathology and affect GABAergic neuronal transmission.

The enteric nervous system of the human and mouse colon at a single-cell resolution

The paper profiles the enteric nervous system of human and mouse colon at single-cell resolution, revealing diverse neuron subsets and shared transcriptional programs between species.