Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
C. Motozono, M. Toyoda, T. S. Tan, H. Hamana, Y. Aritsu, Y. Miyashita, H. Oshiumi, K. Nakamura, S. Okada, K. Udaka, M. Kitamatsu, H. Kishi, T. Ueno
bioRxiv · Apr 17, 2022 · PreprintImmunology
I. Kimura, D. Yamasoba, H. Nasser, J. Zahradnik, Y. Kosugi, J. Wu, K. Nagata, K. Uriu, Y. L. Tanaka, J. Ito, R. Shimizu, T. S. Tan, E. P. Butlertanaka, H. Asakura, K. Sadamasu, , K. Sato
This study identifies the S375F mutation in the Omicron spike protein as responsible for its reduced cleavage efficiency, fusogenicity, and rapid spread.
bioRxiv · Apr 3, 2022Microbiology
B. Meng, I. Ferreira, A. Abdullahi, N. Goonawardane, A. Saito, I. Kimura, D. Yamasoba, S. A. Kemp, G. Papa, S. Fatihi, S. Rathore, P. Perera Gerba, T. Ikeda, M. Toyoda, T. S. Tan, , S. Zepeda
This study investigates the immune escape, infectivity, and cell-cell fusion properties of SARS-CoV-2 Omicron BA.1 compared to Delta, showing higher ACE2 affinity and antibody evasion but similar antiviral drug efficacy.
bioRxiv · Dec 17, 2021Microbiology
C. Motozono, M. Toyoda, J. Zahradnik, T. Ikeda, A. Saito, T. S. Tan, I. Ngare, H. Nasser, I. Kimura, K. Uriu, Y. Kosugi, S. Torii, A. Yonekawa, N. Shimono, Y. Nagasaki, , K. Sato
This study identifies two SARS-CoV-2 mutations, L452R and Y453F, that evade HLA-restricted cellular immunity and increase viral infectivity.
bioRxiv · Apr 2, 2021Microbiology
S. Ozono, Y. Zhang, H. Ode, T. S. Tan, K. Imai, K. Miyoshi, S. Kishigami, T. Ueno, Y. Iwatani, T. Suzuki, K. Tokunaga
The paper examines how naturally occurring mutations in SARS-CoV-2 spike proteins affect cell entry via ACE2 and TMPRSS2, finding that the D614G mutation increases infectivity but remains neutralization-sensitive.
Nature Communications · Feb 8, 2021Peer-reviewedMicrobiology