Author

W.-C. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:zebrafish· 1

Frequent Co-Authors

B. P. Sampurna· 1 shared C.-C. Cheng· 1 shared C.-C. Chien· 1 shared C.-C. Kuo· 1 shared C.-H. Yuh· 1 shared C.-L. Hsiao· 1 shared G.-S. Chiu· 1 shared H.-C. Cheng· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

B. P. Sampurna

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Stabilization of AMPK/PFKL/RPIA in the Glycolytic Bodies Transduces IL6/STAT3 Signal in Hepatocarcinogenesis

H.-Y. Hsiao, C.-C. Cheng, Y.-T. Chou, C.-C. Kuo, W.-C. Wang, B. P. Sampurna, Y.-W. Wang, C.-L. Hsiao, J.-Y. Wu, K.-H. Lin, W.-Y. Yang, Y.-H. Lin, K.-H. Gwee, H.-D. Wang, C.-H. Yuh

This study identifies the STAT3/AMPK/PFKL axis in liver cancer, showing how it promotes glycolysis and tumor growth through stabilization of PFKL and RPIA in glycolytic bodies.

bioRxiv · Feb 29, 2024 · PreprintCancer Biology

Hydrogen Sulfide Coordinates Glucose Metabolism Switch through Destabilizing Tetrameric Pyruvate Kinase M2

R.-H. Wang, P.-R. Chen, Y.-T. Chen, Y.-C. Chen, Y.-H. Chu, C.-C. Chien, P.-C. Chien, S.-Y. Lo, Z.-L. Wang, M.-C. Tsou, S.-Y. Chen, G.-S. Chiu, W.-L. Chen, Y.-H. Wu, L. Wang, , K.-T. Lin

This study shows hydrogen sulfide destabilizes PKM2 tetramer through sulfhydration at cysteine 326, rewiring glucose metabolism and inhibiting tumor growth.

bioRxiv · Sep 2, 2023Cancer Biology