Y. Gao

The paper analyzes the urinary proteome of p53 knockout mice to identify differential proteins and their associations with disease pathways.

The paper generates a high-confidence binary protein interaction network for Drosophila using yeast two-hybrid screens and integrates it with existing data to create a comprehensive reference network.

This study shows that sterile soil prebiotics can restore gut microbial diversity and alleviate anxiety-like behavior and intestinal barrier issues caused by antibiotic exposure across generations in mice.

The paper identifies novel ATR-dependent phospho-proteomic targets and reveals new biomarkers and genome maintenance factors through screening with ATR inhibitors.

This study shows that early microbial intervention in newborn calves reduces diarrhea and improves later milk production by altering gut microbiome composition and metabolite profiles.

This study uses time-resolved cryo-EM to visualize the conformational changes in a GPCR-G protein complex during activation, revealing the structural pathway of G protein dissociation.

This paper introduces a Bayesian framework for brain source imaging that jointly estimates low-rank noise and sparse brain activity, outperforming existing methods on simulated and real data.

The paper presents a transcriptome resource analyzing spatiotemporal gene expression in M. truncatula roots during rhizobial inoculation, revealing tissue-specific expression patterns and identifying genes involved in nodule signaling and organogenesis.

This study characterizes urine proteomic changes in active and recovered COVID-19 patients, identifying persistent immune and metabolic alterations and potential biomarkers.

This study shows that endothelial cell lactate promotes BMSC histone lactylation, enhancing osteogenesis and reducing osteoporosis, with exercise increasing lactate to alleviate the condition.

This paper shows that bradyrhizobia retain their preference for N2O reduction over nitrate reduction under carbon starvation, suggesting they can act as N2O sinks in soils.

This study identifies changes in the urine proteome of healthy individuals after massage, finding more significant differences at 2h compared to 24h post-massage.

This study identifies a non-canonical role of LDHB in protecting KRAS-driven lung cancer from ferroptosis by promoting SLC7A11-mediated glutathione metabolism.

This study shows that phage-specific immune responses can reduce the effectiveness of phage therapy targeting VRE in mice, with different phages eliciting varying immune responses.

The paper identifies transcription factors driving distinct CD8+ T cell states and shows their impact on tumor control and immunotherapy.

This study shows that peptide-poloxamine-DNA nanoparticles provide complete protection against lethal SARS-CoV-2 challenge through robust mucosal immunity.

This study determines the cryo-EM structure of human CaV2.3 channels and identifies key residues and interactions involved in channel gating and inactivation.

This paper conducts a bibliometric analysis of cancer alternative splicing research from 2012 to 2021, identifying trends, key institutions, and research areas.

This study observes immune system changes in rat urine proteome after immunization with bovine serum albumin and aluminum hydroxide adjuvant.

The paper presents a structural model of an Alzheimer's Aβ42 oligomer based on solid-state NMR and cryo-EM data, explaining its stability and ion permeability.

This study reports chromosome-level genome sequences of two Leonurus species, providing resources for studying bioactive molecules in medicinal plants.

This paper introduces an Odourgenetic method using Drosophila odorant receptors to non-invasively and rapidly manipulate cellular functions and behavior through inhalation of 2-pentanone.

This study uses urine proteomics to analyze the effects of e-cigarettes on rats, identifying differential proteins and pathways linked to immune, cardiovascular, and respiratory systems.

The paper uses urine proteomics to detect startle-induced changes in rats, identifying differential proteins related to neurotransmitter and glucose transport.

The paper establishes a stable human cell line as a reference for transcriptomic and proteomic studies, showing consistent results across generations and platforms.

This study shows that AHR activation by dietary ligands improves gut barrier function via zinc-dependent pathways, highlighting the role of zinc in AHR signaling and its protective effects against IBD.

The paper presents a chromosome-level genome assembly of T. grandis and identifies genes responsible for gymnosperm-specific sciadonic acid biosynthesis.

This study identifies and characterizes circRNAs in moso bamboo, their biogenesis, function, and response to gibberellins and auxins.

This study identifies Naproxen as a chemical inhibitor of PIN auxin transporters in plants, revealing its mechanism of action through cellular, biochemical, and structural analyses.

This study examines how HE4 contributes to hyperoxia-induced alveolar damage in rats by activating ERK and p65, modulating MMP9 and TIMP1 pathways, and promoting fibrosis.