Y. Matsuo

DNA metabarcoding workflow utilizing nanopore long-read sequencing and consensus generation for rapid identification of fungal taxa with high phylogenetic resolution

Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complex

The paper investigates how the RQT complex decodes ubiquitin signals to clear colliding ribosomes, showing that Cue3 and Rqt4 interact with K63-linked ubiquitin chains.

Clearing of ribosome collisions by the ribosome quality control trigger complex RQT

The paper shows RQT clears collided ribosomes by pulling mRNA to trigger destabilizing conformational transitions for subunit dissociation.

MinION™, a portable long-read sequencer, enables rapid vaginal microbiota analysis in a clinical setting

The paper demonstrates that MinION sequencing enables rapid, high-resolution analysis of vaginal microbiota in a clinical setting, identifying species-level profiles associated with health and disease.

Full-length 16S rRNA gene amplicon analysis of human gut microbiota using MinION™ nanopore sequencing confers species-level resolution

This study compares full-length and short-read 16S rRNA gene sequencing using MinION and conventional methods to assess species-level resolution in human gut microbiota.

Cancerous phenotypes associated with hypoxia-inducible factors are not influenced by the volatile anesthetic isoflurane in renal cell carcinoma

This study examines whether isoflurane affects cancer cell phenotypes linked to hypoxia-inducible factors in renal cell carcinoma, finding no positive influence of isoflurane on these traits.

Rapid bacterial identification by direct PCR amplification of 16S rRNA genes using the MinION™ nanopore sequencer

This study develops a rapid bacterial identification method using MinION sequencing and direct PCR of 16S rRNA genes, improving diagnostic speed and accuracy.

Propofol induces metabolic reprogramming and cell death in a mitochondrial electron transport chain-dependent manner

This study shows propofol causes metabolic reprogramming and cell death by impairing mitochondrial function, specifically complexes I and III, and this effect is exacerbated by preexisting mitochondrial dysfunction.