Author

K. Nishi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:cryo-EM· 1 Research Focus:database / resource· 1 Approach:deep learning· 1

Frequent Co-Authors

K. Hirota· 2 shared Y. Matsuo· 2 shared A. Furumoto· 1 shared A. Ohta· 1 shared A. Okamoto· 1 shared A. Pham· 1 shared A. Roll-Mecak· 1 shared A. Watanabe· 1 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersMicrobiology

K. Hirota

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Nonequilibrium bending fluctuations reveal microtubule mechanics in-vivo and their regulation by glutamylation

K. Nishi, S. Raja, A. Pham, R. Freeman, A. Roll-Mecak, F. C. MacKintosh, C. F. Schmidt

The paper measures microtubule mechanics in living cells using motor-generated forces and shows that polyglutamylation increases microtubule stiffness.

bioRxiv · Oct 26, 2023 · PreprintBiophysics

Analysis of chronic host-aspergilloma interactions using a novel mouse model

R. Hamashima, M. Tashiro, Y. Nakano, H. Namie, Y. Ito, T. Hirayama, K. Takeda, N. Iwanaga, K. Nishi, H. Liu, T. Takazono, T. Tanaka, A. Watanabe, Y. Komohara, A. Furumoto, , K. Izumikawa

This paper develops a novel mouse model of aspergilloma to study host-fungal interactions, revealing Th1/Th17 responses and angiogenesis induced by dead fungal hyphae.

bioRxiv · Oct 6, 2023 · PreprintMicrobiology

DNA metabarcoding workflow utilizing nanopore long-read sequencing and consensus generation for rapid identification of fungal taxa with high phylogenetic resolution

A. Ohta, K. Nishi, K. Hirota, Y. Matsuo

bioRxiv · Apr 14, 2023 · PreprintMicrobiology

Inhibition mechanism of human sterol O-acyltransferase 1 by competitive inhibitor

C. Guan, Y. Niu, S.-C. Chen, Y. Kang, J.-X. Wu, K. Nishi, C. C. Y. Chang, T.-Y. Chang, T. Luo, L. Chen

This study determines the structure of human SOAT1 using cryo-EM and reveals how the inhibitor CI-976 blocks the active site.

bioRxiv · Jan 7, 2020 · PreprintBiochemistry

Propofol induces metabolic reprogramming and cell death in a mitochondrial electron transport chain-dependent manner

C. Sumi, A. Okamoto, H. Tanaka, K. Nishi, M. Kusunoki, T. Shoji, T. Uba, Y. Matsuo, T. Adachi, J.-I. Hayashi, K. Takenaga, K. Hirota

This study shows propofol causes metabolic reprogramming and cell death by impairing mitochondrial function, specifically complexes I and III, and this effect is exacerbated by preexisting mitochondrial dysfunction.

bioRxiv · Nov 16, 2017Pharmacology & Toxicology