Y.-C. Chen

The paper investigates peroxisomal dysfunction in Zellweger Spectrum Disease and shows that overexpressing ATAD1 restores mitochondrial function in patient-derived fibroblasts.

This study investigates the diversity anomaly of Heterotropa in insular versus continental regions by analyzing phylogenetic relationships and floral trait evolution.

This study shows that islet macrophages transition to a reparative state after beta-cell death, producing IGF-1 and supporting insulin secretion.

This study identifies two dimer-dimer interactions and one aggregation mechanism in CCL5 oligomerization using NMR and biophysical analyses.

The paper shows that DNA damage induces heterogeneous transcriptome responses in cancer cells, with distinct transcriptional programs dictating cell fate outcomes such as checkpoint, apoptosis, or chemoresistance.

This study compares the role of host cells and seeded cells in bone regeneration using fluorescently labeled cells in Ds-Red pigs, showing that higher seeded cell density leads to more sustained cell presence and host cell recruitment.

This paper develops a laser-based system to record subcellular neuron activities with high sensitivity, showing that ultrasound can modulate neuron laser emissions.

The paper identifies Ids2 as a regulator of HSP90 chaperone activity, showing that glucose intake inhibits its function, linking nutrient sensing to proteostasis and longevity.

This study develops a 3D culture system for chicken primordial germ cells using chemically defined media, enabling scalable expansion and maintenance of cellular properties.

The paper identifies associations between driver gene mutations and DNA methylation changes across 18 cancer types, enabling tumor subtype classification and revealing pathway-level impacts.

The p38 MAPK pathway coordinates cell growth and cell cycle progression by lengthening G1 in small cells, allowing them more time to grow before their next division.