Author

Z. Amoozgar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

P. Huang· 3 shared D. Fukumura· 2 shared P. Andersson· 2 shared P.-J. Lei· 2 shared R. Jain· 2 shared A. Matsui· 1 shared A. S. Kumar· 1 shared C. Chuang· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCancer Biology

P. Huang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Reprogramming Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy

J. Chen, Z. Amoozgar, X. LIU, S. Aoki, Z. Liu, S. Shin, A. Matsui, Z. Pu, P.-J. Lei, M. Datta, L. Zhu, Z. Ruan, L. Shi, D. Staiculescu, K. Inoue, , D. G. Duda

This paper shows that combining chemotherapy with CTLA-4 blockade reprograms the immune microenvironment of intrahepatic cholangiocarcinoma, enhancing the effectiveness of anti-PD1 therapy.

bioRxiv · Jan 26, 2023Cancer Biology

Breast cancer progression and metastasis to lymph nodes reveals cancer cell plasticity and MHC class II-mediated immune regulation

P.-J. Lei, E. Pereira, P. Andersson, Z. Amoozgar, J. W. V. Wijnbergen, M. J. O'Melia, H. Zhou, S. Chatterjee, W. W. Ho, J. M. Posada, A. S. Kumar, S. Morita, C. Chuang, I. Ergin, D. Jones, , T. P. Padera

This study identifies MHC class II expression in metastatic breast cancer cells and shows its role in immune evasion and tumor progression through IFN-gamma and JAK/STAT signaling.

bioRxiv · Oct 30, 2022Cancer Biology

Combined blockade of VEGF, Angiopoietin-2, and PD1 reprograms glioblastoma endothelial cells into quasi-antigen-presenting cells

Z. Amoozgar, J. Ren, N. Wang, T. P. Uccello, P. Andersson, G. Ferraro, S. Rajan, P. Lei, S. Subudhi, K. Kawaguchi, R. E. Tay, I. L. Gomes Dos Santos, P. Huang, H.-J. Kim, D. Fukumura, R. Jain

This study shows that blocking VEGF, Ang2, and PD1 reprograms GBM endothelial cells into quasi-antigen-presenting cells, enhancing anti-tumor responses and controlling edema.

bioRxiv · Sep 3, 2022 · PreprintCancer Biology