Author

Ellen V. Backhouse

UK Dementia Research InstituteORCID 0000-0001-5083-9945Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:GWAS / association mapping· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew Mark McIntoshiD· 2 shared Heather Clare WhalleyiD· 2 shared Joanna Marguerite WardlawiD· 2 shared Simon R. CoxiD· 2 shared Adele M. TayloriD· 1 shared Alejo J. Nevado‐HolgadoiD· 1 shared Aleks StolicyniD· 1 shared Andrew David GrotzingeriD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenetics

Andrew Mark McIntoshORCID

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2 papers

Recent·Most cited

Lifetime brain atrophy estimated from a single MRI: measurement characteristics and genome-wide correlates

Anna Elisabeth Fürtjes, Isabelle Francesca Foote, Charley Xia, Gail Davies, Joanna E. Moodie, Adele M. Taylor, David C M Liewald, Paul H. Redmond, Janie Corley, Andrew Mark McIntosh, Heather Clare Whalley, Susana Muñoz Maniega, Maria del Carmen Valdés Hernández, Ellen V. Backhouse, Karen J. Ferguson, , Simon R. Cox

This paper evaluates methods to estimate lifetime brain atrophy from a single MRI scan and identifies genetic correlates, finding that the residual method best captures brain shrinkage and has strong heritability.

Nature Communications · Jul 21, 2025Peer-reviewedGenetics

Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health

Danni A. Gadd, Robert Francis Hillary, Daniel L. McCartney, Liu Shi, Aleks Stolicyn, Neil Robertson, Rosie May Walker, Robert I. McGeachan, Archie I Campbell, Xueyi Shen, Miruna C. Barbu, Claire Green, Stewart W. Morris, Mathew A. Harris, Ellen V. Backhouse, , Riccardo Emilio Marioni

The paper identifies DNA methylation and proteomic markers associated with brain health through integrated methylome and phenome analyses.

Nature Communications · Aug 9, 2022Peer-reviewedGenetic & Genomic Medicine