Kristin C. Gunsalus

This study shows avocado-derived compounds alter lipid homeostasis and lipid droplet profiles in C. elegans by disrupting mitochondrial function and lipid metabolism.

This study examines genome evolution in parthenogenetic nematodes, revealing chromosome fusions, rearrangements, and evidence of rare sexual reproduction events.

This study identifies how eLOTUS domains activate Vasa by promoting its RNA and ATP binding through a charged disordered sequence, revealing a localization-dependent regulatory mechanism.

The paper identifies PAC-1 and LGL-1 as redundant inhibitors of apical polarity in C. elegans embryonic epidermis through genetic analysis.

TeloSearchLR identifies novel telomere repeat motifs using long sequencing reads, improving detection in cases where short-read tools fail.

Seek-a-Seq detects microbial nucleic acids at attomolar concentrations using fluorescent hybridization without PCR or enzymes.

This study identifies avocado fatty alcohols/acetates (AFAs) as a new class of anthelmintics that target lipid metabolism in parasitic nematodes.

The paper shows that the Omicron Spike protein's positive electrostatic surface enhances ACE2 binding and antibody evasion, contributing to its higher transmissibility.

The paper identifies LOTR-1, a C. elegans protein with LOTUS and Tudor domains, which interacts with ZNFX-1 to regulate small RNA processing in the germline.

This study shows that β-actin levels influence chromatin remodeling activities and 3D genome architecture in mouse embryonic fibroblasts.

Pheniqs 2.0 improves barcode decoding accuracy and confidence estimation for combinatorial indexing in sequencing data.

NASQAR provides a web-based platform with tools for analyzing and visualizing high-throughput sequencing data, targeting non-programming researchers.

The paper quantifies sex-specific small RNAomes in C. elegans and identifies sex- and tissue-specific differences in RNAi resistance.

BioSAILs provides a workflow management system for high-throughput data analysis, supporting multiple software stacks and execution environments.

The paper investigates piRNA biogenesis in nematodes, showing that piRNA upstream motifs are derived from snRNA promoter elements and that piRNA production depends on RNA polymerase II pausing and chromatin structure.

Pheniqs improves sequence demultiplexing by incorporating quality scores and error probability estimation, achieving higher accuracy and speed.