Author
The University of Texas Southwestern Medical CenterORCID 0000-0001-9835-6889Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Jinhai Yu, Tong Guo, Arun K. Das Gupta…·Rodney Elwood Infante
This study shows that tumor-secreted GDF15 drives cachexia in STK11/LKB1-mutated NSCLC, and blocking GDF15 reduces cachexia symptoms in mice.
Shayna Elizabeth Thomas-Jardin, Shruthy Suresh, Ariana Arce…·Kathryn A. O’Donnell
The paper shows that the integrated stress response (ISR) coordinates the translation of PD-L1 and CD155, two immune checkpoint proteins, in lung cancer, and suggests combining ISR inhibition with PD-1 blockade as a therapeutic strategy.
Ryan R Kowash, Manoj Kumar Sabnani, Laura T. Gray…·Esra A. Akbay
This paper develops a novel MICA/B-targeting antibody that enhances NK cell activity and shows therapeutic efficacy in KRAS LKB1 mutant lung cancer models.