Author

Vedat Sari

University of VirginiaORCID 0000-0002-3891-5869Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:C. elegans· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Alaattin KayaiD· 3 shared Rohil HameediD· 3 shared Andrey A. ParkhitkoiD· 1 shared Bushra Mehkri· 1 shared Charles Evans· 1 shared Derek C. ProsseriD· 1 shared Elizabeth Malaugh· 1 shared Hetian Su· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMolecular Biology

Alaattin KayaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Color-dependent foraging in C. elegans integrates chromoprotein photosensitization with bacterial metabolic cues

Rohil Hameed, Vedat Sari, Yang Yue, Zhenwen Yu, С. А. Кошкин, Charles Evans, Andrey A. Parkhitko, Scott F. Leiser, Alaattin Kaya

This study shows C. elegans uses chromoprotein photosensitization and bacterial metabolic cues to prefer red over blue food, independent of light and photoreceptors.

bioRxiv · Aug 29, 2026 · PreprintMolecular Biology

NPC1 deficiency engages a lysosome - genome - immune program linked to neurodegeneration and cellular aging signatures

Morteza Abyadeh, Masoumeh Zarei‐Kheirabadi, Pei‐Chi Hou, Vedat Sari, Kyubin Lee, Rohil Hameed, Bushra Mehkri, Elizabeth Malaugh, Jason Newton, Tomasz Kordula, Yuh‐Hwa Wang, Alaattin Kaya

This study shows that NPC1 deficiency causes genomic instability and immune activation linked to neurodegeneration and aging, and identifies Fingolimod as a potential treatment.

bioRxiv · Jul 13, 2026 · PreprintMolecular Biology

Engineering ATP Import in Yeast Uncovers a Synthetic Route to Extend Cellular Lifespan

Naci Oz, Hetian Su, Vedat Sari, Praveen K. Patnaik, Rohil Hameed, Jong Hee Song, Derek C. Prosser, Vyacheslav M. Labunskyy, Vadim N. Gladyshev, Nan Hao, Alaattin Kaya

This paper shows that manipulating intracellular ATP levels in yeast through synthetic ATP import extends cellular lifespan and reveals distinct metabolic pathways involved in aging.

bioRxiv · Apr 14, 2025 · PreprintMolecular Biology