Marco Cambiaghi

Oligodendroglial deletion of the microcephaly gene Cit-k disrupts cortical connectivity and cognitive function

This study shows that deleting Cit-k in oligodendroglia causes hypomyelination and cognitive deficits in mice, independent of neuronal defects.

Retinal network dysfunction precedes structural degeneration in severe GUCA1A cone-rod dystrophy

This study shows that retinal network dysfunction occurs before structural degeneration in severe GUCA1A cone-rod dystrophy, suggesting an early therapeutic window.

Transcranial direct current stimulation (tDCS) promotes myelin repair and plasticity in the mouse motor cortex

This study shows that anodal tDCS promotes myelin repair and enhances oligodendroglial survival and maturation in the injured motor cortex of mice, while also inducing myelin plasticity in the uninjured cortex.

Integrative transcriptomic and metabolic analyses of the mammalian hibernating brain identifies a key role for succinate dehydrogenase in ischemic tolerance

Neural precursor cells contribute to decision-making by tuning striatal connectivity via secretion of IGFBPL-1

This study identifies a non-neurogenic role of SVZ-eNPCs in regulating striatal GABAergic transmission and decision-making through IGFBPL-1 secretion.