Montserrat Carrascal

MHC II-expressing bone marrow megakaryocytes are noncanonical antigen presenting cells and activate CD4+ T cells ex vivo

The paper identifies MHC II-expressing bone marrow megakaryocytes as noncanonical antigen-presenting cells capable of activating CD4+ T cells and modulating immune responses.

Specific killing of Ewing sarcoma by TCR-T cells targeting public neogene-encoded antigens

The paper demonstrates that TCR-T cells targeting neogene-encoded antigens can specifically kill Ewing sarcoma cells in vitro and in vivo.

Mitochondrial Proteome of Affected Neurons in a Mouse Model of Leigh Syndrome

The paper uses a novel viral tool to isolate mitochondria from affected neurons in a mouse model of Leigh Syndrome, revealing proteomic and acetylomic changes associated with mitochondrial dysfunction.