Author

Tatu Pantsar

University of Eastern FinlandORCID 0000-0002-0369-2909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Aditi AgrawaliD· 1 shared Amrita OjhaiD· 1 shared Antonis E. KoromilasiD· 1 shared Antti PosoiD· 1 shared Atsuo T. SasakiiD· 1 shared Benjamin A. PinskyiD· 1 shared Brajendra K. TripathiiD· 1 shared Carlos R. Azpilcueta‐NicolasiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

Aditi AgrawalORCID

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2 papers

Recent·Most cited

eIF2B Selectively Anchors and Activates Mutant KRAS

Hyungdong Kim, Shiqi Diao, Kwang‐Jin Cho, Hyun-Ro Lee, Junchen Liu, Pascal F. Egea, Tatu Pantsar, Milla Kurki, Nour Ghaddar, Shuo Wang, Jia Yi Zou, Mehdi Amiri, Ritchel B. Gannaban, John F. Hancock, Kylie M. Rice, , Antonis E. Koromilas

This paper shows eIF2B activates mutant KRAS by forming a complex with SOS at the plasma membrane and regulating glycosphingolipid biosynthesis.

bioRxiv · Nov 10, 2025 · PreprintCancer Biology

PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2

Marwah Karim, Manjari Mishra, Chieh‐Wen Lo, Sirle Saul, Halise Busra Cagirici, Manon Gourdelier, Luca Ghita, Amrita Ojha, Tran Do Hoang Nhu, Aditi Agrawal, Connor McGraw, Michael P. East, Karen Anbro Gammeltoft, Malaya Kumar Sahoo, Nancie A. Mooney, , Shirit Einav

RMC-113 inhibits PIP4K2C and PIKfyve, reversing SARS-CoV-2-induced autophagic flux impairment and showing antiviral effects.

Nature Communications · Jul 10, 2025Peer-reviewedMicrobiology