Prg4+ fibro-adipogenic progenitors in muscle are crucial for bone fracture repair
Qi He, Jiawei Lu, Qiushi Liang, Lutian Yao, Tingfang Sun, Huan Wang, Michael P. Duffy, Xi Jiang, Yuewei Lin, Jihyung Lee, Jaimo Ahn, Nathaniel A. Dyment, Foteini Mourkioti, Joel D. Boerckel, Ling Qin
This paper identifies Prg4+ fibro-adipogenic progenitors in muscle as critical for bone fracture repair by transforming into bone cells and promoting healing.
Proceedings of the National Academy of Sciences · Jul 29, 2025Peer-reviewedCell Biology