Sooryanarayana Varambally

NNMT Loss Drives Cancer Progression by enhancing SAM availability for mTORC1 Signaling and Chromatin Methylation

This study identifies NNMT as a tumor suppressor in prostate cancer that regulates SAM availability, mTORC1 signaling, and chromatin methylation, revealing a therapeutic strategy using dietary methionine restriction and mTORC1 inhibition.

UALCAN Mobile, an app for cancer proteogenomic data analysis.

UALCAN Mobile provides cancer proteogenomic data analysis through an app, enabling users to explore gene, protein, and epigenetic changes across multiple cancer types and stratifications.

Skeletal Metastasis of Prostate Cancer Is Augmented by Activation of EphA2 Noncanonical Signaling and Ligand-Deficient Bone Microenvironment

This study shows EphA2 overexpression and loss of its ligands in prostate cancer promote bone metastasis through noncanonical signaling in a ligand-deficient bone microenvironment.

Comparative transcriptome analyses reveal genes associated with SARS-CoV-2 infection of human lung epithelial cells

The paper compares transcriptome data from SARS-CoV-2 and other respiratory virus infections in human lung epithelial cells to identify genes and pathways associated with SARS-CoV-2 infection.