Author

Richard Thomas Scott

IVIRMA GlobalORCID 0000-0002-2572-3980Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Alison CampbelliD· 1 shared Ángel MartíniD· 1 shared Berna SözeniD· 1 shared Chuanxin ZhangiD· 1 shared Emre U SeliiD· 1 shared Han ZhaoiD· 1 shared Keliang WuiD· 1 shared Magdalena Zernicka‐GoetziD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Alison CampbellORCID

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1 paper

Recent·Most cited

Mechanism of cell polarisation and first lineage segregation in the human embryo

Meng Zhu, Marta N. Shahbazi, Ángel Martín, Chuanxin Zhang, Berna Sözen, Máté Borsos, Rachel S. Mandelbaum, Richard J. Paulson, Matteo A. Molè, Marga Esbert, Richard Thomas Scott, Alison Campbell, Simon B. Fishel, Viviana Gradinaru, Han Zhao, , Magdalena Zernicka‐Goetz

This study identifies the mechanism of first lineage segregation in human embryos through cell polarisation, showing it occurs at the 8-cell stage via F-actin and Par complex polarisation, with PLC activation and GATA3 regulation.

bioRxiv · Sep 23, 2020 · PreprintDevelopmental Biology