Author

Nicholas Wong

University Health NetworkORCID 0000-0002-2831-2415Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Nicholas Wong3 papers · University of California San Diego

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Kristin J. HopeiD· 2 shared Amanda TajikiD· 1 shared Amélie Fradet‐TurcotteiD· 1 shared Andy G.X. ZengiD· 1 shared Anne‐Claude GingrasiD· 1 shared Ava Keyvani ChahiiD· 1 shared Brendon SealeiD· 1 shared Brian A. YeeiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Kristin J. HopeORCID

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2 papers

Recent·Most cited

Stress Granules Underlie Acute Myeloid Leukemia Stem Cell Survival and Stress Adaptation

Amanda Tajik, Emily Tsao, Soheil Jahangiri, Brendon Seale, Brian A. Yee, Jack T. Naritomi, Zaldy Balde, Séverine Cathelin, Ava Keyvani Chahi, Lance Li, He Tian Chen, Nicholas Wong, Lina Liu, Pratik Joshi, Steven Moreira, , Kristin J. Hope

This study identifies stress granules as critical for AML stem cell survival and stress adaptation, revealing their role in gene regulation and potential as therapeutic targets.

bioRxiv · Jan 14, 2025 · PreprintCancer Biology

Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes

Maëva Devoucoux, Victoire Fort, Gabriel Khelifi, Joshua Xu, Nader Alerasool, Maxime Galloy, Nicholas Wong, Gaëlle Bourriquen, Amélie Fradet‐Turcotte, Mikko Taipale, Kristin J. Hope, Samer M. I. Hussein, Jacques Côté

This paper characterizes the ZMYND11-MBTD1 fusion protein's role in oncogenesis by mislocalizing the NuA4/TIP60 complex to gene bodies, altering transcription and splicing, particularly of the MYC oncogene.

Cell Reports · Jun 1, 2022Peer-reviewedMolecular Biology