Author

Mengmeng Wang

Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center; Dallas, TX, 75235, USAORCID 0000-0002-2908-6480Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Mengmeng Wang1 paper · Xuzhou Medical College

Biology Disciplines

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Physiology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Zhijie LiiD· 2 shared Albert Qiang· 1 shared Ali Ahmed Diaz· 1 shared Amaey BellaryiD· 1 shared Andrew C. LuiD· 1 shared Bo GuiD· 1 shared Boyuan Li· 1 shared Daniel J. SiegwartiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSynthetic Biology

Zhijie LiORCID

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2 papers

Recent·Most cited

Engineered protein circuits for cancer therapy

Andrew C. Lu, Lukas Moeller, Stephen Moore, Kevin Ho, Victoria Tobin, Albert Qiang, Evan Zhang, Zhijie Li, Mengmeng Wang, Shiyu Xia, Mark W. Budde, Haley Larson, Ali Ahmed Diaz, Bo Gu, James M. Linton, , Michael B. Elowitz

This paper engineers protease-based protein circuits that selectively kill RAS-mutant cancer cells and suppress tumors, showing resistance reduction and cytotoxicity independent of oncogene addiction.

bioRxiv · Apr 16, 2025 · PreprintSynthetic Biology

Mechanistic basis for protection against fatty liver disease by CIDEB loss-of-function mutations

Qiyu Zeng, Satish Patel, Xun Wang, Meng-Hsiung Hsieh, Zhijie Li, Xiongzhao Ren, Jingjing Wang, Dohun Kim, Shili Li, Xinping Gu, Greg Mannino, Gianna Maggiore, Xiangyi Fang, Lin Li, Min Zhu, , Hao Zhu

This study investigates how CIDEB loss-of-function mutations protect against fatty liver disease by enhancing β-oxidation through ATGL and PPARα activation.

bioRxiv · Apr 1, 2025 · PreprintPhysiology