Author

Graham Anderson

University of BirminghamORCID 0000-0002-2917-4085Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Andrea BaconiD· 2 shared Adéla ČepkováiD· 1 shared Adriano Giorgio RossiiD· 1 shared Andrea CorsinottiiD· 1 shared Andrea White· 1 shared Andrew S MacDonald· 1 shared Anne Wolf· 1 shared Atsunori TsuchiyaiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

Andrea BaconORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

IL4Ra Controls The Medullary Dwell Time Of Mature Thymocytes By Scheduling Their Release From The Thymus

Graham Anderson, Kieran D James, Andrea White, Fabrina M Gaspal, Sonia M Parnell, Andrea Bacon, Stefano A Colombo, Andrew S MacDonald, Anne Wolf, Maria Milani, Thomas Langmann, William E Jenkinson

This study shows that IL4Ra signaling in SP thymocytes prolongs their medullary dwell time, enhancing their maturation and functional capabilities.

bioRxiv · Nov 9, 2026 · PreprintImmunology

Regulatory T cell stability determines the efficiency of bile duct regeneration during cholangitis.

Naruhiro Kimura, Man Chun Wong, Ben Higgins, Gareth R. Hardisty, Pei-Chi Huang, Matamoana Muller, Maxym Besh, Daniel A. Patten, Timothy James Kendall, Prakash Ramachandran, Adriano Giorgio Rossi, Graham Anderson, Shishir Shetty, David R. Withers, Atsunori Tsuchiya, , Wei‐Yu Lu

This study shows that regulatory T cells (Tregs) influence bile duct regeneration during cholangitis, and their stability is critical for reducing fibrosis and inflammation.

Cell Reports · Nov 1, 2025Peer-reviewedImmunology

Watch-breaker: establishment of a microwell array-based miniaturized thymic organoid model suitable for high throughput applications.

Viktoria Major, Sam Palmer, Paul Rouse, Jan Morys, Timothy Henderson, Tania Hübscher, Joanna Sweetman, Andrea Bacon, Chengrui An, Guiyun Qiu, Yu Wang, Andrea Corsinotti, Justyna Cholewa-Waclaw, Stephen Jonathan Chapman, Matthias P. Lütolf, , Clare C. Blackburn

The paper introduces a microwell array-based thymic organoid model that supports T-cell development and is suitable for high-throughput analysis.

Cell Reports · Apr 15, 2025Peer-reviewedImmunology

Claudin 1-mediated positioning of DC1 to mTECs is essential for antigen transfer-coupled DC1 maturation and maintenance of central tolerance

Jiří Březina, Tomáš Brabec, David Machac, Matouš Vobořil, Ondřej Ballek, Jan Pačes, Vojtěch Sýkora, Kristina Jancovicova, Evgeny Valter, Katarina Kovacova, Jasper E. Manning, Valerie Tahtahova, Adéla Čepková, Martina Dobešová, Jan Dobeš, , Dominik Filipp

The study identifies Claudin 1 on DC1s as essential for their positioning near mTECs, facilitating antigen transfer and DC1 maturation, which maintains central tolerance.

bioRxiv · Mar 15, 2025 · PreprintImmunology