Sonia Cruciani

This paper introduces m6ABasecaller, a method for de novo basecalling of m6A modifications at single molecule and single nucleotide resolution using nanopore sequencing.

The paper uses rRNA modification patterns to identify tissue and tumor-specific signatures, showing their potential as diagnostic biomarkers.

The paper uses single nucleus RNA-seq to analyze the hippocampus of a Down syndrome mouse model, identifying transcriptomic changes and a novel long-non-coding gene involved in cognitive phenotypes.

This study maps 2'-O-methylation sites and identifies C/D box snoRNAs in Drosophila rRNAs, showing limited stress-induced variation in methylation levels.

This paper shows that using high-accuracy nanopore RNA basecalling models improves detection of RNA modifications, read mappability, and basecalling accuracy.

The paper introduces a method to quantify RNA modifications using nanopore sequencing, revealing novel modification sites and dynamics in yeast under environmental stress.

The paper investigates the subcellular relocalization of TRMT1 and TRMT1L during neuronal activation and identifies their role in RNA modification dynamics and neuronal plasticity.