Eben Alsberg

4D Biomimetic Morphing Hydrogel Scaffold via Biaxial Gradient Programming

This paper develops a biaxial gradient-programmed 4D hydrogel system that enables precise, non-uniform shape morphing and supports cell-laden biofabrication for biomimetic tissue engineering.

Self-Actuating 4D Cell-Strand Bioprinting

This paper introduces a self-actuating 4D cell-strand bioprinting platform that generates complex tissue architectures through autonomous cell contractile force-driven morphing.

Reprogrammable 4D Tissue Engineering Hydrogel Scaffold via Reversible Ion Printing

This paper develops a reprogrammable hydrogel scaffold using ion-transfer printing to enable shape transformations in bioconstructs, demonstrating 3D-to-3D shape conversions in engineered cartilage-like tissues.

Cell Contractile Forces Drive Spatiotemporal Morphing in 4D Bioprinted Living Constructs

This paper develops a 4D bioprinting method using cell-contractile forces to drive shape changes in cell-laden constructs, demonstrating simultaneous morphing and chondrogenic differentiation.

In situ cell condensation-based cartilage tissue engineering via immediately implantable high-density stem cell core and rapidly degradable shell microgels

This paper develops core/shell microgels for in situ cartilage tissue engineering, enabling immediate implantation and spontaneous fusion of cell condensates without prior in vitro culture.

A 4D Bio-Kirigami Strategy for Engineering Complex Tissue Curvatures

This paper introduces a bio-Kirigami strategy to create dynamic, transformable tissue-like structures using hydrogels with controlled deformation modes.

Cyr61 delivery promotes angiogenesis during bone fracture repair

This study shows that Cyr61 delivery enhances angiogenesis during bone fracture repair, particularly in fractures with stable fixation, and may have therapeutic potential for poor vascularization.

Biofabrication of engineered tissues by 3D bioprinting of tissue specific high cell-density bioinks

This study develops tissue-specific high cell-density bioinks for 3D bioprinting, enabling the formation of multi-phase tissues with controlled architecture.

Photocrosslinkable and biodegradable hydrogels for the controlled delivery of exosomes

This study develops photocrosslinkable, biodegradable alginate hydrogels for controlled exosome delivery, showing that degradation rates influence exosome release kinetics.

In situ cell-only bioprinting of patterned prevascular tissue into bioprinted high-density stem cell-laden microgel bioinks for vascularized bone tissue regeneration

This paper develops a bioink for 3D bioprinting that enables in situ creation of vascularized bone tissue constructs in mouse calvarial defects.

Three-dimensional tissue platform co-laid with native collagen fibers and cells for phenotypic screening of stem cell interactions

This study develops a 3D tissue platform with collagen and stem cells to screen cell-cell and cell-matrix interactions, showing enhanced vascularization and identifying pathways affecting vasculogenesis and ASD models.

Cell Contractile Force-Mediated Morphodynamical Tissue Engineering via 4D Printed Degradable Hydrogel Scaffolds

This study introduces a 4D printed hydrogel scaffold that uses cell contractile forces to drive tissue morphogenesis, enabling programmed shape transformations and scaffold-free tissue constructs.

Clickable PEG-norbornene microgels support suspension bioprinting and microvascular assembly

This study develops clickable PEGNB microbeads that enable suspension bioprinting and microvascular self-assembly for engineering hierarchical vasculature.

Non-adhesive alginate hydrogels support growth of pluripotent stem cell-derived intestinal organoids

This study shows that non-adhesive alginate hydrogels support the growth and differentiation of human intestinal organoids, comparable to Matrigel.