Author

Obed Akwasi Aning

Agency for Science, Technology and ResearchORCID 0000-0002-4002-2787Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Abdul AkhiriD· 1 shared Angelo FreiiD· 1 shared Ann-Britt Schäfer· 1 shared Çağrı ÖzsaniD· 1 shared Chit Fang CheokiD· 1 shared Deepanshi SaxenaiD· 1 shared Dong Shin Park· 1 shared Enrico G. PetrettoiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Abdul AkhirORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A Platinum Butterfly Effect: Small Changes Turn an Anticancer Drug into a Non-toxic Metalloantibiotic with In Vivo Efficacy

Çağrı Özsan, Ann-Britt Schäfer, Abdul Akhir, Obed Akwasi Aning, Sofia Fulgencio, Rahul Maitra, Rupa Rani, Deepanshi Saxena, Fredrik Westerlund, Sidharth Chopra, Michaela Wenzel, Angelo Frei

This paper describes the development of a platinum-based antibiotic, Pt1, which shows potent antibacterial activity against resistant Staphylococcus aureus strains and demonstrates in vivo efficacy in a murine infection model.

npj Antimicrobials and Resistance · May 8, 2026Peer-reviewedMicrobiology

Expanded huntingtin CAG repeats disrupt the balance between neural progenitor expansion and differentiation in human cerebral organoids

Jinqiu Zhang, Jolene Ooi, Kagistia Hana Utami, Sarah R. Langley, Obed Akwasi Aning, Dong Shin Park, Magdalena Renner, Shiming Ma, Chit Fang Cheok, Juergen A. Knoblich, Florent Ginhoux, Enrico G. Petretto, Mahmoud A. Pouladi

This study shows that expanded CAG repeats in HTT disrupt neural progenitor expansion and differentiation in human cerebral organoids, suggesting abnormal neurodevelopment in Huntington disease.

bioRxiv · Nov 26, 2019 · PreprintDevelopmental Biology