Author

Thomas J. Evans

University of GlasgowORCID 0000-0002-4140-6352Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Thomas J. Evans1 paper

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:genome assembly· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alistair Leanord· 1 shared Andrew J. RoeiD· 1 shared Andrew J. SmithiD· 1 shared Carla JohnsoniD· 1 shared Cheng‐Hock TohiD· 1 shared Christopher A. MoxoniD· 1 shared Dagmara McGuinnessiD· 1 shared Edwin Alexander YatesiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Alistair Leanord

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2 papers

Recent·Most cited

Bacterial histone-like proteins released during antibiotic treatment mediate vascular injury in meningococcal sepsis.

Dagmara McGuinness, Carla Johnson, Leandro Lemgruber, Fadil A. Bidmos, Edwin Alexander Yates, Jeremy E. Turnbull, Tom J. Evans, Rebecca E. McHugh, Andrew J. Roe, Gill R. Douce, Andrew J. Smith, Roisin Ure, Cheng‐Hock Toh, Simon Timothy Abrams, Jethro Adam Herberg, , Christopher A. Moxon

Antibiotic treatment of meningococcal and other sepsis causative bacteria triggers the release of histone-like proteins (HLPs) that damage the endothelium and drive coagulopathy, but these effects can be neutralized by non-anticoagulant heparins or anti-HLP antibodies.

bioRxiv · Jul 16, 2026 · PreprintMicrobiology

Integrated population clustering and genomic epidemiology with PopPIPE

Martin P. McHugh, Samuel Horsfield, Johanna von Wachsmann, Jacqueline Toussaint, Kerry A. Pettigrew, Elzbieta Czarniak, Thomas J. Evans, Alistair Leanord, Luke Tysall, Stephen H. Gillespie, Kate E. Templeton, Matthew T. G. Holden, Nicholas J. Croucher, John A. Lees

PopPIPE clusters bacterial populations and detects transmission events using reference-free methods, outperforming traditional approaches in nosocomial outbreak analysis.

Microbial Genomics · Apr 28, 2025Peer-reviewedBioinformatics