Author
Institute of Molecular BiologyORCID 0000-0002-5036-2419Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Ida J. Isolehto, Lizaveta Pshanichnaya, Diego Javier Páez-Moscoso…·René F. Ketting
The paper identifies a novel regulatory mechanism involving proteolytic processing of N-terminal intrinsically disordered regions in C. elegans Argonaute proteins, which controls small RNA selectivity and activity.
Jan Schreier, Fridolin Kielisch, René F. Ketting
This study identifies the roles of argonaute proteins in RNAi inheritance in C. elegans, showing HRDE-1 is required for silencing while WAGO-3 is essential for inheritance.
Rajani Kanth Gudipati, Kathrin Braun, Foivos Gypas…·Helge Großhans
The paper shows that proteolytic processing of Argonaute proteins by DPF-3 regulates small RNA association, maintaining genome integrity and fertility in C. elegans.
Maria Placentino, António Miguel de Jesus Domingues, Jan Schreier…·René F. Ketting
The paper identifies PID-2 and related proteins as essential for establishing and maintaining RNAe in C. elegans embryos through interactions with eTudor domain proteins and proteolysis.