Motohiro Sekiya

Multimodal phenotyping reveals plant-food-related dietary information in serum Raman spectra of community-dwelling Japanese adults

The paper links dietary patterns with serum Raman spectra and metabolomics in Japanese adults, showing dietary information is distributed across complementary phenotypic layers.

CH-related Mutant ASXL1 Promotes Atherosclerosis in Mice via Dysregulated Innate Immunity

This study shows that ASXL1 mutations in mice promote atherosclerosis by dysregulating innate immunity through impaired inhibition of NF-κB signaling.

Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at ER monitoring and regulating fatty acids

The paper shows RHBDL4 cleaves SREBP-1c at the ER, with its activity modulated by fatty acid types, and demonstrates its role in lipid homeostasis.

Disentangling the biological information encoded in disordered mitochondrial morphology through its rapid elicitation by iCMM

This study introduces iCMM, a method to rapidly manipulate mitochondrial morphology, revealing its rapid impact on biological information reconstitution.