Author

Subhash B. Arya

University of MichiganORCID 0000-0002-5671-8666Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Carole A. ParentiD· 3 shared Samuel P. Collie· 2 shared Amanda Huber· 1 shared Andrew D. PattersoniD· 1 shared Anitha Vijay Mallappa· 1 shared Brendon M. BakeriD· 1 shared Carlos Ichiro Kasano-CamonesiD· 1 shared Costas Andreas LyssiotisiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCancer Biology

Carole A. ParentORCID

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Author profile →

3 papers

Recent·Most cited

Fatty acids in the tumor microenvironment reprogram neutrophils to induce immunosuppression via adenosine

Rashi Singhal, Nina W. Zhang, Zheng Hong Lee, Hannah Noelle Bell, Prarthana Dalal, Sumeet A. Solanki, Wesley Huang, Ryan James Rebernick, Peter Sajjakulnukit, Himani Jasewicz, Roshan Kumar, Nikhil Kumar Kotla, Amanda Huber, Anitha Vijay Mallappa, Subhash B. Arya, , Yatrik Madhukar Shah

This study identifies a fatty acid-driven neutrophil-adenosine axis that promotes immunosuppression in colorectal cancer and shows that targeting adenosine receptors can enhance immunotherapy responses.

bioRxiv · Apr 6, 2026 · PreprintCancer Biology

cPLA2α Targeting to Exosomes Connects Nuclear Deformation to LTB4-Signaling During Neutrophil Chemotaxis

Subhash B. Arya, Fatima Jordan-Javed, Kristen Loesel, Yehyun Choi, Samuel P. Collie, Lauren E. Hein, Brendon M. Baker, Euisik Yoon, Carole A. Parent

This study shows cPLA2α localizes to exosomes during neutrophil chemotaxis, linking nuclear deformation to LTB4 signaling and motility.

Science Advances · Feb 20, 2026Peer-reviewedCell Biology

Neutrophils secrete exosome-associated DNA to resolve sterile acute inflammation

Subhash B. Arya, Samuel P. Collie, Yang Xu, Martin Fernandez, Jonathan Z. Sexton, Shyamal Mosalaganti, Pierre A. Coulombe, Carole A. Parent

This study shows neutrophils release nuclear DNA via exosomes to resolve sterile inflammation, with implications for treating inflammatory diseases.

Nature Cell Biology · May 22, 2025Peer-reviewedImmunology