Sumeet A. Solanki

This study identifies a heme-SDH-CoQ axis that helps colorectal cancer cells resist iron-induced oxidative stress and cell death.

This study identifies a fatty acid-driven neutrophil-adenosine axis that promotes immunosuppression in colorectal cancer and shows that targeting adenosine receptors can enhance immunotherapy responses.

This study shows that dietary cysteine improves intestinal stem cell repair through IL-22 from CD8+ T cells.

This study investigates the role of labile iron pool dynamics in ferroptosis in colorectal cancer cells and finds that exogenous iron supplementation reduces cell viability without measurable LIP expansion during ferroptosis.

This study recharacterizes RSL3 as a broad selenoprotein inhibitor, showing its potential as a therapeutic target for colorectal cancer by inducing ferroptosis.

This study identifies Fmo5's sex-specific role in goblet cell maturation and mucus barrier formation in the intestine, with severe effects in female mice.

The paper investigates how enriched versus impoverished housing conditions affect tumorigenesis in a mouse model of colitis-associated colon cancer, finding enriched housing reduces tumor burden.