Suzanne J. Baker

CD11c+ microglia promote dysfunctional T cell activation in diffuse midline glioma

This study identifies CD11c+ microglia as a key driver of T cell dysfunction in diffuse midline glioma through genetic and orthotopic mouse models.

Dominant Malignant Clones Leverage Lineage Restricted Epigenomic Programs to Drive Ependymoma Development

This study identifies specific developmental epigenomic states that enable ZFTA-RELA-driven ependymoma formation and reveals how these states shape tumor progression.

CD155 regulates tumor growth and immune evasion in diffuse midline glioma.

This study identifies CD155 as a key regulator of tumor growth and immune evasion in diffuse midline glioma, showing that targeting CD155 or its downstream target FOXM1 can inhibit tumor progression.

A single-cell and single-nucleus RNA-seq toolbox for fresh and frozen human tumors

The paper develops a toolbox for scRNA-Seq and snRNA-Seq of fresh and frozen human tumors, testing it across eight tumor types and optimizing protocols for different tissue characteristics.

XenoCP: Cloud-based BAM cleansing tool for RNA and DNA from Xenograft

XenoCP is a cloud-based tool that removes mouse reads from xenograft BAM files to improve RNA-seq and WGS analysis accuracy.