Sai Saroja Kolluru

Aging Fly Cell Atlas Identifies Exhaustive Aging Features at Cellular Resolution

The paper presents an aging Drosophila cell atlas, identifies cell type-specific aging patterns, and shows ribosomal gene expression as a conserved aging predictor.

The Tabula Sapiens: a multiple organ single cell transcriptomic atlas of humans

Nearly 500,000 cells from 24 human tissues, many from one donor, characterize over 400 cell types and enable within-donor study of T-cell clones, B-cell mutation rates and splicing.

Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer's model

The paper shows reducing USP16 improves neural precursor cell function and memory in an Alzheimer's model by affecting Cdkn2a and BMP signaling.

Fly Cell Atlas: a single-cell transcriptomic atlas of the adult fruit fly

The paper creates a single-cell transcriptomic atlas of the adult fruit fly, identifying over 250 cell types and analyzing gene signatures and sexual dimorphism across tissues.

Coronary blood vessels from distinct origins converge to equivalent states during mouse and human development

The paper shows that coronary endothelial cells in mouse and human hearts initially show lineage-specific transcriptional differences but later become influenced by location, with adult cells becoming more homogeneous.

A cell atlas of the fly kidney

The paper characterizes cell types in the fly kidney using snRNA-seq and identifies new clusters, markers, and signaling networks, linking them to mammalian and planarian kidney structures.

Single-cell transcriptomes of developing and adult olfactory receptor neurons in Drosophila

The paper generates single-cell transcriptomes of Drosophila olfactory receptor neurons across development and adulthood, revealing stable receptor expression and cell-type-specific transcriptomic features.

Temporal evolution of single-cell transcriptomes of Drosophila olfactory projection neurons

The paper analyzes single-cell transcriptomes of Drosophila olfactory projection neurons across developmental stages to identify transcriptomic changes and cellular diversity patterns.

Cerebellar nuclei evolved by repeatedly duplicating a conserved cell type set

The paper identifies a conserved cell type set in cerebellar nuclei across species and shows how it was duplicated to form new regions, with a shift in dominance in humans.

Serotonin Neurons in the Dorsal and Medial Raphe Nuclei: from Single-Cell Transcriptomes to Whole-Brain Projections

The paper characterizes serotonin neuron subtypes in the dorsal and medial raphe nuclei using single-cell RNA sequencing and maps their axonal projections to understand their functional diversity.