Matthijn R. J. Vos

Structural determinants of endopilus assembly, stability and functional specificity in bacterial type II secretion

The paper investigates the structural basis of endopilus assembly, stability, and functional specificity in bacterial type II secretion systems using comparative analysis of two pathogens.

Uncompromised, multimodal, multiscale structural analysis of the hierarchically organization in mineralized tissues

The paper presents a correlative imaging workflow for multiscale structural and chemical analysis of mineralized tissues, revealing a plywood-like collagen architecture and phosphate-rich mineral platelets in zebrafish scales.

Nitrate-responsive Mycobacterial Intracytoplasmic Membranes dampen Inflammation during Mycobacterium tuberculosis Infection

This study identifies nitrate-induced intracytoplasmic membranes in Mycobacterium tuberculosis that help dampen inflammation during infection.

Bridging the resolution gap in cryo-CLEM by introducing cryo-SXT: cryo-CLXEM

This paper introduces cryo-SXT as an intermediate technique to bridge the resolution gap in cryo-CLEM by providing 3D cellular context to cryo-ET datasets.

TYPE THREE SECRETION SYSTEM-INDUCED MECHANOPORATION OF VACUOLAR MEMBRANES

This study identifies mechanoporation via the Type Three Secretion System as a mechanism by which Shigella flexneri breaches vacuolar membranes to access the cytosol.

3D Variable Analysis Reveal a Hidden Conformational Dynamics Controlling Ammonia Transport in Human Asparagine Synthetase

The paper uses 3DVA and MD simulations to reveal that Arg-142 in ASNS acts as a gate controlling ammonia transport through an intramolecular tunnel.