Bradley A. Maron

Targeting NEDD9-SH3 with a Covalent Peptide Controls Endothelial Phenotype

This study develops a covalent peptide targeting NEDD9-SH3 to inhibit endothelial migration and fibroproliferative remodeling in PAH by stabilizing the RT loop and modulating sulfatase-1 activity.

Peruvian Population Genomics: Unraveling the Genetic Landscape and Admixture Dynamics of Urban Populations

The paper analyzes genome-wide data from 432 Peruvian urban individuals to reveal fine-scale population structure, admixture dynamics, and demographic patterns shaped by ancient and recent events.

Lactate transport inhibition therapeutically reprograms fibroblast metabolism in experimental pulmonary fibrosis

The paper shows that inhibiting lactate transporters MCT1 and MCT4 reduces myofibroblast differentiation and pulmonary fibrosis in vitro and in vivo.

COVID-19: Viral-host interactome analyzed by network based-approach model to study pathogenesis of SARS-CoV-2 infection.

The paper analyzes the viral-host interactome of SARS-CoV, MERS-CoV, and HCoV-229E using a network-based approach to predict SARS-CoV-2 pathogenesis.