Tohru Terada

Reprogramming protein interfaces between adenylation and carrier protein domains in nonribosomal peptide synthetases

This study reprograms protein interfaces between adenylation and carrier protein domains in NRPSs to enable non-cognate pairings and enhance natural product production.

A planar dimer of bovine ATP synthase

The paper identifies a planar dimeric form of bovine ATP synthase with minimal membrane bending, contrasting with canonical dimers that induce significant curvature.

CGRig: a rigid-body protein model with residue-level interaction sites for long-time and large-scale protein assembly simulation

CGRig is a rigid-body protein model that enables efficient simulation of large-scale protein assembly while preserving residue-level interaction specificity.

hnRNPA2B1 Modulates Early TIA1 Recruitment into Stress Granules through an RNA-Dependent Assembly Mechanism

High-throughput prediction of protein-protein interactions uncovers hidden molecular networks in biosynthetic gene clusters

The paper predicts protein-protein interactions in biosynthetic gene clusters to uncover hidden molecular networks and functional enzyme complexes.

UNKAI: A protein functional identity prediction model based on ESM-C latent representations and the attention mechanism

This paper introduces a deep learning model that predicts if two proteins catalyze the same reaction using ESM-C latent representations and attention mechanisms, outperforming existing methods.

Enhanced prediction of protein functional identity through the integration of sequence and structural features

The paper develops a method to predict if two proteins catalyze the same reaction by integrating sequence and structural features, outperforming existing approaches.

Fc-independent SARS-CoV-2 infection-enhancing antibodies decouple N-terminal and receptor-binding domains by cross-linking neighboring spikes

This study shows that certain SARS-CoV-2 antibodies enhance infection by cross-linking spike proteins, causing NTD-RBD domain decoupling without needing the Fc region.

Comprehensive computational analysis of the SRK-SP11 molecular interaction underlying self-incompatibility in Brassicaceae using improved structure prediction for cysteine-rich proteins

The paper improves structure prediction for cysteine-rich proteins in Brassicaceae and analyzes eSRK-SP11 binding modes across haplotypes.