A long-deletion mouse model of Williams syndrome reveals Ncf1-dependent modulation of vascular and neural phenotypes
Laurens W. J. Bosman, Hamid el Azzouzi, Lieke Kros, Nicole van Vliet, Yanto R. Ridwan, Stéphanie Dijkhuizen, Erika Sabel-Goedknegt, Bastian S. Generowicz, Martijn C. Sierksma, Dick Jaarsma, Manuele Novello, M. W. C. Snoeren, Emma Kretschmann, Danique Broere, Rocco Caliandro, , Chris I. De Zeeuw
This paper develops a long-deletion mouse model of Williams syndrome to study vascular and neural phenotypes, finding that Ncf1 modulates both cardiovascular and neuropsychological symptoms.
bioRxiv · Oct 30, 2023 · PreprintSystems Biology